Druggability, molecular targets, and nanocarrier delivery of natural triterpenoid celastrol against chronic diseases
Celastrol is an active compound from the root of Tripterygium wilfordii Hook F that shows great potential in the treatment of inflammation, cancer, neurodegeneration, diabetes, and obesity. However, the clinical application of celastrol has been hindered by its low bioavailability and severe syste...
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| Main Authors: | Chi Lui Chan, Yilu Sun, Xiaowen Mao, Hansen Chen, Jia Zhao, Jianhui Rong |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Compuscript Ltd
2024-10-01
|
| Series: | Acta Materia Medica |
| Online Access: | https://www.scienceopen.com/hosted-document?doi=10.15212/AMM-2024-0044 |
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