Targeting immune cellular populations and transcription factors: unraveling the therapeutic potential of JQF for NAFLD

Targeting immune cellular populations and transcription factors: unraveling the therapeutic potential of JQF for NAFLD

BackgroundNon-alcoholic fatty liver disease (NAFLD) constitutes the most prevalent chronic liver disease worldwide. Progression to non-alcoholic steatohepatitis (NASH), the immune cell reservoir within the liver undergoes remodeling, exacerbating liver inflammation and potentially leading to liver f...

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Main Authors: Lijuan Zhou, Jingyi Zhao, Kaile Ma, Rui Hao, Chensi Yao, Xiaowen Gou, Chuanxi Tian, Li Wan, Min Li, Xiaolin Tong
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Immunology
Subjects:
single-cell RNA sequencing
spatial transcriptomics
non-alcoholic fatty liver disease
macrophages
T cells
traditional Chinese medicine
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1445924/full
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