Multi-omics of a model bacterial consortium deciphers details of chitin decomposition in soil

ABSTRACT Soil microorganisms interact to carry out decomposition of complex organic carbon and nitrogen compounds, such as chitin, but the high diversity and complexity of the soil microbiome and habitat have posed a challenge to elucidating such interactions. Here, we sought to address this challen...

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Main Authors: Ryan McClure, Albert Rivas-Ubach, Kim K. Hixson, Yuliya Farris, Marci Garcia, Robert Danczak, Michelle Davison, Vanessa L. Paurus, Janet K. Jansson
Format: Article
Language:English
Published: American Society for Microbiology 2025-07-01
Series:mBio
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Online Access:https://journals.asm.org/doi/10.1128/mbio.00404-25
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author Ryan McClure
Albert Rivas-Ubach
Kim K. Hixson
Yuliya Farris
Marci Garcia
Robert Danczak
Michelle Davison
Vanessa L. Paurus
Janet K. Jansson
author_facet Ryan McClure
Albert Rivas-Ubach
Kim K. Hixson
Yuliya Farris
Marci Garcia
Robert Danczak
Michelle Davison
Vanessa L. Paurus
Janet K. Jansson
author_sort Ryan McClure
collection DOAJ
description ABSTRACT Soil microorganisms interact to carry out decomposition of complex organic carbon and nitrogen compounds, such as chitin, but the high diversity and complexity of the soil microbiome and habitat have posed a challenge to elucidating such interactions. Here, we sought to address this challenge by analysis of a model soil consortium (MSC-2) consisting of eight soil bacterial species. Our aim was to elucidate the specific roles of the member species during chitin metabolism. Samples were collected from MSC-2 incubated in chitin-enriched soil over 3 months. Multi-omics was used to understand how the community composition, transcripts, proteins, and chitin decomposition shifted over time. The data clearly and consistently revealed a temporal shift during chitin decomposition with defined contributions by individual species. A Streptomyces genus member (sp001905665) was a key player in early steps of chitin decomposition, with other MSC-2 members being central in carrying out later steps. These results illustrate how multi-omics applied to a defined consortium untangles the interactions between soil microorganisms.IMPORTANCEAlthough soil microorganisms carry out decomposition of organic matter in soil, the details are unclear due to the complexity of the soil microbiome and the heterogeneity of the soil habitat. Understanding carbon decomposition is of vital importance to determine how the soil carbon cycle functions. This is especially important with regard to understanding the fertility of soils and their ability to support plant growth. To overcome these challenges, we investigated in considerable detail a model soil community during its decomposition of a typical soil organic molecule—chitin. By using a multi-omics approach, we were able to decipher community interactions during chitin breakdown. This information provides a basis for understanding how more complex soil microbial communities interact in nature.
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spelling doaj-art-c7390b77fe004d7b87d0d79a7bfce7852025-08-20T03:28:41ZengAmerican Society for MicrobiologymBio2150-75112025-07-0116710.1128/mbio.00404-25Multi-omics of a model bacterial consortium deciphers details of chitin decomposition in soilRyan McClure0Albert Rivas-Ubach1Kim K. Hixson2Yuliya Farris3Marci Garcia4Robert Danczak5Michelle Davison6Vanessa L. Paurus7Janet K. Jansson8Biological Sciences Division, Pacific Northwest National Laboratory, Richland, Washington, USAEnvironmental and Molecular Sciences Division (EMSL), Pacific Northwest National Laboratory, Richland, Washington, USAEnvironmental and Molecular Sciences Division (EMSL), Pacific Northwest National Laboratory, Richland, Washington, USABiological Sciences Division, Pacific Northwest National Laboratory, Richland, Washington, USABiological Sciences Division, Pacific Northwest National Laboratory, Richland, Washington, USABiological Sciences Division, Pacific Northwest National Laboratory, Richland, Washington, USABiological Sciences Division, Pacific Northwest National Laboratory, Richland, Washington, USAPhysical and computational Sciences Division, Pacific Northwest National Laboratory, Richland, Washington, USABiological Sciences Division, Pacific Northwest National Laboratory, Richland, Washington, USAABSTRACT Soil microorganisms interact to carry out decomposition of complex organic carbon and nitrogen compounds, such as chitin, but the high diversity and complexity of the soil microbiome and habitat have posed a challenge to elucidating such interactions. Here, we sought to address this challenge by analysis of a model soil consortium (MSC-2) consisting of eight soil bacterial species. Our aim was to elucidate the specific roles of the member species during chitin metabolism. Samples were collected from MSC-2 incubated in chitin-enriched soil over 3 months. Multi-omics was used to understand how the community composition, transcripts, proteins, and chitin decomposition shifted over time. The data clearly and consistently revealed a temporal shift during chitin decomposition with defined contributions by individual species. A Streptomyces genus member (sp001905665) was a key player in early steps of chitin decomposition, with other MSC-2 members being central in carrying out later steps. These results illustrate how multi-omics applied to a defined consortium untangles the interactions between soil microorganisms.IMPORTANCEAlthough soil microorganisms carry out decomposition of organic matter in soil, the details are unclear due to the complexity of the soil microbiome and the heterogeneity of the soil habitat. Understanding carbon decomposition is of vital importance to determine how the soil carbon cycle functions. This is especially important with regard to understanding the fertility of soils and their ability to support plant growth. To overcome these challenges, we investigated in considerable detail a model soil community during its decomposition of a typical soil organic molecule—chitin. By using a multi-omics approach, we were able to decipher community interactions during chitin breakdown. This information provides a basis for understanding how more complex soil microbial communities interact in nature.https://journals.asm.org/doi/10.1128/mbio.00404-25soil microbiomemodel soil consortium-2chitinchitin decompositionmulti-omicsmetabolomics
spellingShingle Ryan McClure
Albert Rivas-Ubach
Kim K. Hixson
Yuliya Farris
Marci Garcia
Robert Danczak
Michelle Davison
Vanessa L. Paurus
Janet K. Jansson
Multi-omics of a model bacterial consortium deciphers details of chitin decomposition in soil
mBio
soil microbiome
model soil consortium-2
chitin
chitin decomposition
multi-omics
metabolomics
title Multi-omics of a model bacterial consortium deciphers details of chitin decomposition in soil
title_full Multi-omics of a model bacterial consortium deciphers details of chitin decomposition in soil
title_fullStr Multi-omics of a model bacterial consortium deciphers details of chitin decomposition in soil
title_full_unstemmed Multi-omics of a model bacterial consortium deciphers details of chitin decomposition in soil
title_short Multi-omics of a model bacterial consortium deciphers details of chitin decomposition in soil
title_sort multi omics of a model bacterial consortium deciphers details of chitin decomposition in soil
topic soil microbiome
model soil consortium-2
chitin
chitin decomposition
multi-omics
metabolomics
url https://journals.asm.org/doi/10.1128/mbio.00404-25
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