Modern View on the Problem of Choosing a Vaccine against Hepatitis B

The problem of the discrepancy between serotypes of the circulating strains of hepatitis B virus and serotype of the HBsAg in the vaccine is discussed. The results of published scientific studies show that hepatitis B vaccines containing HBsAg serotype ad provide good, but not optimal, protection ag...

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Main Authors: V. P. Chulanov, T. A. Semenenko, I. V. Karandashova, S. V. Komarova, D. S. Kostyushev, A. P. Suslov, E. V. Volchkova
Format: Article
Language:Russian
Published: Numikom LLC 2017-08-01
Series:Эпидемиология и вакцинопрофилактика
Subjects:
Online Access:https://www.epidemvac.ru/jour/article/view/298
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author V. P. Chulanov
T. A. Semenenko
I. V. Karandashova
S. V. Komarova
D. S. Kostyushev
A. P. Suslov
E. V. Volchkova
author_facet V. P. Chulanov
T. A. Semenenko
I. V. Karandashova
S. V. Komarova
D. S. Kostyushev
A. P. Suslov
E. V. Volchkova
author_sort V. P. Chulanov
collection DOAJ
description The problem of the discrepancy between serotypes of the circulating strains of hepatitis B virus and serotype of the HBsAg in the vaccine is discussed. The results of published scientific studies show that hepatitis B vaccines containing HBsAg serotype ad provide good, but not optimal, protection against heterologous serotypes of the virus. The authors conclude that the use of vaccines containing HBsAg serotype typical for given territory is a priority. Further in-depth studies on this issue are needed to clarify the available scientific evidence.
format Article
id doaj-art-c72b1fd2a08342a7bd0cc7d047894a7b
institution Kabale University
issn 2073-3046
2619-0494
language Russian
publishDate 2017-08-01
publisher Numikom LLC
record_format Article
series Эпидемиология и вакцинопрофилактика
spelling doaj-art-c72b1fd2a08342a7bd0cc7d047894a7b2025-08-20T03:43:46ZrusNumikom LLCЭпидемиология и вакцинопрофилактика2073-30462619-04942017-08-01164657210.31631/2073-3046-2017-16-4-65-72297Modern View on the Problem of Choosing a Vaccine against Hepatitis BV. P. Chulanov0T. A. Semenenko1I. V. Karandashova2S. V. Komarova3D. S. Kostyushev4A. P. Suslov5E. V. Volchkova6Federal State Institution of Science «Central Research Institute of Epidemiology» Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing; Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University of the Ministry of Healthcare of the Russian FederationFederal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University of the Ministry of Healthcare of the Russian Federation; Federal State Budgetary Institution «National Research Center for Epidemiology and Microbiology named after the Honorable Academician N.F. Gamalei» of Ministry of Healthcare of the Russian FederationFederal State Institution of Science «Central Research Institute of Epidemiology» Federal Service for Surveillance on Consumer Rights Protection and Human WellbeingFederal State Institution of Science «Central Research Institute of Epidemiology» Federal Service for Surveillance on Consumer Rights Protection and Human WellbeingFederal State Institution of Science «Central Research Institute of Epidemiology» Federal Service for Surveillance on Consumer Rights Protection and Human WellbeingFederal State Institution of Science «Central Research Institute of Epidemiology» Federal Service for Surveillance on Consumer Rights Protection and Human WellbeingFederal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University of the Ministry of Healthcare of the Russian FederationThe problem of the discrepancy between serotypes of the circulating strains of hepatitis B virus and serotype of the HBsAg in the vaccine is discussed. The results of published scientific studies show that hepatitis B vaccines containing HBsAg serotype ad provide good, but not optimal, protection against heterologous serotypes of the virus. The authors conclude that the use of vaccines containing HBsAg serotype typical for given territory is a priority. Further in-depth studies on this issue are needed to clarify the available scientific evidence.https://www.epidemvac.ru/jour/article/view/298вирус гепатита ввакцинацияпрофилактиказаболеваемостьсубтипсеротипштаммантигенная детерминантаhepatitis b virusvaccinationpreventionmorbiditysubtypeserotypestrainantigenic determinant
spellingShingle V. P. Chulanov
T. A. Semenenko
I. V. Karandashova
S. V. Komarova
D. S. Kostyushev
A. P. Suslov
E. V. Volchkova
Modern View on the Problem of Choosing a Vaccine against Hepatitis B
Эпидемиология и вакцинопрофилактика
вирус гепатита в
вакцинация
профилактика
заболеваемость
субтип
серотип
штамм
антигенная детерминанта
hepatitis b virus
vaccination
prevention
morbidity
subtype
serotype
strain
antigenic determinant
title Modern View on the Problem of Choosing a Vaccine against Hepatitis B
title_full Modern View on the Problem of Choosing a Vaccine against Hepatitis B
title_fullStr Modern View on the Problem of Choosing a Vaccine against Hepatitis B
title_full_unstemmed Modern View on the Problem of Choosing a Vaccine against Hepatitis B
title_short Modern View on the Problem of Choosing a Vaccine against Hepatitis B
title_sort modern view on the problem of choosing a vaccine against hepatitis b
topic вирус гепатита в
вакцинация
профилактика
заболеваемость
субтип
серотип
штамм
антигенная детерминанта
hepatitis b virus
vaccination
prevention
morbidity
subtype
serotype
strain
antigenic determinant
url https://www.epidemvac.ru/jour/article/view/298
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AT svkomarova modernviewontheproblemofchoosingavaccineagainsthepatitisb
AT dskostyushev modernviewontheproblemofchoosingavaccineagainsthepatitisb
AT apsuslov modernviewontheproblemofchoosingavaccineagainsthepatitisb
AT evvolchkova modernviewontheproblemofchoosingavaccineagainsthepatitisb