Limbic Encephalitis following Allogeneic Hematopoietic Stem Cell Transplantation

A woman with myelodysplastic syndrome (MDS) was treated with allogeneic hematopoietic stem cell transplantation (allo-HSCT). 65 days after the transplantation, she developed fatigue and central neurological symptoms. Clinical workup including magnetic resonance imaging (MRI) and cerebrospinal fluid...

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Main Authors: Silje Johansen, Jostein Kråkenes, C. A. Vedeler, Anette Margrethe Storstein, Håkon Reikvam
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Case Reports in Immunology
Online Access:http://dx.doi.org/10.1155/2022/4174755
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author Silje Johansen
Jostein Kråkenes
C. A. Vedeler
Anette Margrethe Storstein
Håkon Reikvam
author_facet Silje Johansen
Jostein Kråkenes
C. A. Vedeler
Anette Margrethe Storstein
Håkon Reikvam
author_sort Silje Johansen
collection DOAJ
description A woman with myelodysplastic syndrome (MDS) was treated with allogeneic hematopoietic stem cell transplantation (allo-HSCT). 65 days after the transplantation, she developed fatigue and central neurological symptoms. Clinical workup including magnetic resonance imaging (MRI) and cerebrospinal fluid (CSF) examination revealed findings suspicious for limbic encephalitis (LE), successfully treated with intravenous immunoglobulins and intravenous corticosteroids. Although a rare complication after allo-HSCT, physicians should be aware of neurological symptoms that develop throughout the transplantation course.
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institution Kabale University
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language English
publishDate 2022-01-01
publisher Wiley
record_format Article
series Case Reports in Immunology
spelling doaj-art-c728c0b295734bb4ad16a52053f2a34a2025-02-03T01:22:56ZengWileyCase Reports in Immunology2090-66172022-01-01202210.1155/2022/4174755Limbic Encephalitis following Allogeneic Hematopoietic Stem Cell TransplantationSilje Johansen0Jostein Kråkenes1C. A. Vedeler2Anette Margrethe Storstein3Håkon Reikvam4Department of MedicineDepartment of RadiologyDepartment of Clinical MedicineDepartment of NeurologyDepartment of MedicineA woman with myelodysplastic syndrome (MDS) was treated with allogeneic hematopoietic stem cell transplantation (allo-HSCT). 65 days after the transplantation, she developed fatigue and central neurological symptoms. Clinical workup including magnetic resonance imaging (MRI) and cerebrospinal fluid (CSF) examination revealed findings suspicious for limbic encephalitis (LE), successfully treated with intravenous immunoglobulins and intravenous corticosteroids. Although a rare complication after allo-HSCT, physicians should be aware of neurological symptoms that develop throughout the transplantation course.http://dx.doi.org/10.1155/2022/4174755
spellingShingle Silje Johansen
Jostein Kråkenes
C. A. Vedeler
Anette Margrethe Storstein
Håkon Reikvam
Limbic Encephalitis following Allogeneic Hematopoietic Stem Cell Transplantation
Case Reports in Immunology
title Limbic Encephalitis following Allogeneic Hematopoietic Stem Cell Transplantation
title_full Limbic Encephalitis following Allogeneic Hematopoietic Stem Cell Transplantation
title_fullStr Limbic Encephalitis following Allogeneic Hematopoietic Stem Cell Transplantation
title_full_unstemmed Limbic Encephalitis following Allogeneic Hematopoietic Stem Cell Transplantation
title_short Limbic Encephalitis following Allogeneic Hematopoietic Stem Cell Transplantation
title_sort limbic encephalitis following allogeneic hematopoietic stem cell transplantation
url http://dx.doi.org/10.1155/2022/4174755
work_keys_str_mv AT siljejohansen limbicencephalitisfollowingallogeneichematopoieticstemcelltransplantation
AT josteinkrakenes limbicencephalitisfollowingallogeneichematopoieticstemcelltransplantation
AT cavedeler limbicencephalitisfollowingallogeneichematopoieticstemcelltransplantation
AT anettemargrethestorstein limbicencephalitisfollowingallogeneichematopoieticstemcelltransplantation
AT hakonreikvam limbicencephalitisfollowingallogeneichematopoieticstemcelltransplantation