Spotted Fever: An Undercover Cause of Hemophagocytic Lymphohistiocytosis in the Immediate Postpartum
Hemophagocytic lymphohistiocytosis (HLH) is characterized by a dysregulated activation of the immune system that causes fever, cytopenias, organomegalies, and hemophagocytosis. There are infectious, neoplastic, rheumatologic, and miscellaneous causes. Rickettsioses are a neglected cause of HLH. We r...
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| Format: | Article |
| Language: | English |
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Wiley
2022-01-01
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| Series: | Case Reports in Infectious Diseases |
| Online Access: | http://dx.doi.org/10.1155/2022/3348393 |
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| author | Karen Aida Ibarra Stone Jose Gabriel Solis Enrique Blanco-Lemus Jose Malagón-Rangel Guadalupe Gordillo-Perez |
| author_facet | Karen Aida Ibarra Stone Jose Gabriel Solis Enrique Blanco-Lemus Jose Malagón-Rangel Guadalupe Gordillo-Perez |
| author_sort | Karen Aida Ibarra Stone |
| collection | DOAJ |
| description | Hemophagocytic lymphohistiocytosis (HLH) is characterized by a dysregulated activation of the immune system that causes fever, cytopenias, organomegalies, and hemophagocytosis. There are infectious, neoplastic, rheumatologic, and miscellaneous causes. Rickettsioses are a neglected cause of HLH. We report a confirmed case of an immunocompetent woman in Mexico with postpartum HLH secondary to spotted fever. We did a review of the literature for search of similar cases. The association between these two diseases was found in postmortem studies, unrelated to postpartum. This diagnosis should be considered in all patients with HLH without an evident cause in areas of epidemiological risk. |
| format | Article |
| id | doaj-art-c72331b80c24451fbcf46fd05002333f |
| institution | OA Journals |
| issn | 2090-6633 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Infectious Diseases |
| spelling | doaj-art-c72331b80c24451fbcf46fd05002333f2025-08-20T02:19:44ZengWileyCase Reports in Infectious Diseases2090-66332022-01-01202210.1155/2022/3348393Spotted Fever: An Undercover Cause of Hemophagocytic Lymphohistiocytosis in the Immediate PostpartumKaren Aida Ibarra Stone0Jose Gabriel Solis1Enrique Blanco-Lemus2Jose Malagón-Rangel3Guadalupe Gordillo-Perez4Hospital de EspecialidadesHospital de EspecialidadesHospital de CardiologiaHospital de EspecialidadesUnidad de Investigación de Enfermedades Infecciosas y ParasitariasHemophagocytic lymphohistiocytosis (HLH) is characterized by a dysregulated activation of the immune system that causes fever, cytopenias, organomegalies, and hemophagocytosis. There are infectious, neoplastic, rheumatologic, and miscellaneous causes. Rickettsioses are a neglected cause of HLH. We report a confirmed case of an immunocompetent woman in Mexico with postpartum HLH secondary to spotted fever. We did a review of the literature for search of similar cases. The association between these two diseases was found in postmortem studies, unrelated to postpartum. This diagnosis should be considered in all patients with HLH without an evident cause in areas of epidemiological risk.http://dx.doi.org/10.1155/2022/3348393 |
| spellingShingle | Karen Aida Ibarra Stone Jose Gabriel Solis Enrique Blanco-Lemus Jose Malagón-Rangel Guadalupe Gordillo-Perez Spotted Fever: An Undercover Cause of Hemophagocytic Lymphohistiocytosis in the Immediate Postpartum Case Reports in Infectious Diseases |
| title | Spotted Fever: An Undercover Cause of Hemophagocytic Lymphohistiocytosis in the Immediate Postpartum |
| title_full | Spotted Fever: An Undercover Cause of Hemophagocytic Lymphohistiocytosis in the Immediate Postpartum |
| title_fullStr | Spotted Fever: An Undercover Cause of Hemophagocytic Lymphohistiocytosis in the Immediate Postpartum |
| title_full_unstemmed | Spotted Fever: An Undercover Cause of Hemophagocytic Lymphohistiocytosis in the Immediate Postpartum |
| title_short | Spotted Fever: An Undercover Cause of Hemophagocytic Lymphohistiocytosis in the Immediate Postpartum |
| title_sort | spotted fever an undercover cause of hemophagocytic lymphohistiocytosis in the immediate postpartum |
| url | http://dx.doi.org/10.1155/2022/3348393 |
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