Enantioselective Cleavage of meso-Nitrodiol Diacetates by an Esterase Concentrate from Fresh Pig Liver: Preparation of Useful Nitroaliphatic Building Blocks for EPC Syntheses

Diacetates of meso-2-nitro-1,3-diols, readily available from nitroalkanes and aldehydes, are saponified to crystalline monoacetates of > 97% ee by pig liver esterase (PLE). A general discussion of this type of EPC synthesis (EPC: enantiomerically pure compounds) is given, and a specific example...

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Bibliographic Details
Main Authors: Dieter Seebach, Martin Eberle
Format: Article
Language:deu
Published: Swiss Chemical Society 1986-09-01
Series:CHIMIA
Online Access:https://www.chimia.ch/chimia/article/view/9749
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