Advancing a Patient- and Carer-Centered Approach for the Clinical Development of New Therapeutics for Aneurysmal Subarachnoid Hemorrhage: Insights From a Qualitative Study

Aneurysmal subarachnoid hemorrhage (aSAH) is characterized by a high rate of fatality and high risk of secondary brain injury. More treatment options are needed to improve outcomes. There are very few reports in the medical literature involving patient experience of aSAH, which is known for its unex...

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Main Authors: Sonya Abraham, Silvia Amaro, Ellyn Getz, Sylvia Herget, Gregory J. Kato
Format: Article
Language:English
Published: Advocate Aurora Health 2025-04-01
Series:Journal of Patient-Centered Research and Reviews
Subjects:
Online Access:https://institutionalrepository.aah.org/cgi/viewcontent.cgi?article=2119&context=jpcrr
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author Sonya Abraham
Silvia Amaro
Ellyn Getz
Sylvia Herget
Gregory J. Kato
author_facet Sonya Abraham
Silvia Amaro
Ellyn Getz
Sylvia Herget
Gregory J. Kato
author_sort Sonya Abraham
collection DOAJ
description Aneurysmal subarachnoid hemorrhage (aSAH) is characterized by a high rate of fatality and high risk of secondary brain injury. More treatment options are needed to improve outcomes. There are very few reports in the medical literature involving patient experience of aSAH, which is known for its unexpected onset and profound medical impact. Improved understanding of this patient experience would help make future clinical research more patient centered. To this end, we convened an advisory board consisting of aSAH patients and care partners in the United States. Participants emphasized the critical role that care partners play during hospitalization and in accessing supportive resources and rehabilitative care. Recommendations included improving the accessibility of clinical research information during the consent process with sensitivity to the stress and cognitive challenges of patients who have had an aSAH. Participants also recommended prioritizing in-person – either on-site or at-home – as opposed to remote follow-up visits because in-person communication can be easier for those recovering from aSAH. Insights from this study could be invaluable for the clinical development of new therapeutics for aSAH and other acute neurological conditions, with the goal of better meeting the needs of patients and their families during clinical research participation.
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spelling doaj-art-c71b7dff8a7c4e6a8196762dd37ac0d02025-08-20T02:24:46ZengAdvocate Aurora HealthJournal of Patient-Centered Research and Reviews2330-06982025-04-01122828610.17294/2330-0698.2119Advancing a Patient- and Carer-Centered Approach for the Clinical Development of New Therapeutics for Aneurysmal Subarachnoid Hemorrhage: Insights From a Qualitative StudySonya Abraham0https://orcid.org/0000-0002-9976-9009Silvia Amaro1Ellyn Getz2https://orcid.org/0009-0001-4956-5235Sylvia Herget3Gregory J. Kato4https://orcid.org/0000-0003-4465-3217CSL BehringCSL BehringCSL BehringCSL BehringCSL BehringAneurysmal subarachnoid hemorrhage (aSAH) is characterized by a high rate of fatality and high risk of secondary brain injury. More treatment options are needed to improve outcomes. There are very few reports in the medical literature involving patient experience of aSAH, which is known for its unexpected onset and profound medical impact. Improved understanding of this patient experience would help make future clinical research more patient centered. To this end, we convened an advisory board consisting of aSAH patients and care partners in the United States. Participants emphasized the critical role that care partners play during hospitalization and in accessing supportive resources and rehabilitative care. Recommendations included improving the accessibility of clinical research information during the consent process with sensitivity to the stress and cognitive challenges of patients who have had an aSAH. Participants also recommended prioritizing in-person – either on-site or at-home – as opposed to remote follow-up visits because in-person communication can be easier for those recovering from aSAH. Insights from this study could be invaluable for the clinical development of new therapeutics for aSAH and other acute neurological conditions, with the goal of better meeting the needs of patients and their families during clinical research participation.https://institutionalrepository.aah.org/cgi/viewcontent.cgi?article=2119&context=jpcrrsubarachnoid hemorrhagecaregiversinformed consentpatient participation
spellingShingle Sonya Abraham
Silvia Amaro
Ellyn Getz
Sylvia Herget
Gregory J. Kato
Advancing a Patient- and Carer-Centered Approach for the Clinical Development of New Therapeutics for Aneurysmal Subarachnoid Hemorrhage: Insights From a Qualitative Study
Journal of Patient-Centered Research and Reviews
subarachnoid hemorrhage
caregivers
informed consent
patient participation
title Advancing a Patient- and Carer-Centered Approach for the Clinical Development of New Therapeutics for Aneurysmal Subarachnoid Hemorrhage: Insights From a Qualitative Study
title_full Advancing a Patient- and Carer-Centered Approach for the Clinical Development of New Therapeutics for Aneurysmal Subarachnoid Hemorrhage: Insights From a Qualitative Study
title_fullStr Advancing a Patient- and Carer-Centered Approach for the Clinical Development of New Therapeutics for Aneurysmal Subarachnoid Hemorrhage: Insights From a Qualitative Study
title_full_unstemmed Advancing a Patient- and Carer-Centered Approach for the Clinical Development of New Therapeutics for Aneurysmal Subarachnoid Hemorrhage: Insights From a Qualitative Study
title_short Advancing a Patient- and Carer-Centered Approach for the Clinical Development of New Therapeutics for Aneurysmal Subarachnoid Hemorrhage: Insights From a Qualitative Study
title_sort advancing a patient and carer centered approach for the clinical development of new therapeutics for aneurysmal subarachnoid hemorrhage insights from a qualitative study
topic subarachnoid hemorrhage
caregivers
informed consent
patient participation
url https://institutionalrepository.aah.org/cgi/viewcontent.cgi?article=2119&context=jpcrr
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