Oncolytic herpes simplex viruses designed for targeted treatment of EGFR-bearing tumors

Oncolytic herpes simplex viruses (oHSVs) have emerged as leading cancer therapeutic agents. Effective oHSV virotherapy may ultimately require both intratumoral and systemic vector administration to target the primary tumor and distant metastases. An attractive approach to enhancing oHSV tumor specif...

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Bibliographic Details
Main Authors: Selene Ingusci, Bonnie L. Hall, Justus B. Cohen, Joseph C. Glorioso
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Molecular Therapy: Oncology
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Online Access:http://www.sciencedirect.com/science/article/pii/S2950329924000031
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