Neuroplasticity in Alzheimer's disease: a therapeutic alternative at the molecular level

The neuroplasticity mechanisms of the organism form the basis of dissimilar therapies that seek to potentiate such effects to achieve relative improvement in a large number of neurodegenerative diseases. Included within this high number of conditions, Alzheimer's disease stands out, due to its...

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Main Authors: Noel Jesús Niebla Gómez, Rodolfo Javier Rivero Morey, Víctor René Navarro Machado, Mariangel González León, Amanda Martínez Pérez
Format: Article
Language:Spanish
Published: Centro Provincial de Información de Ciencias Médicas. Cienfuegos 2020-08-01
Series:Medisur
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Online Access:http://medisur.sld.cu/index.php/medisur/article/view/4426
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author Noel Jesús Niebla Gómez
Rodolfo Javier Rivero Morey
Víctor René Navarro Machado
Mariangel González León
Amanda Martínez Pérez
author_facet Noel Jesús Niebla Gómez
Rodolfo Javier Rivero Morey
Víctor René Navarro Machado
Mariangel González León
Amanda Martínez Pérez
author_sort Noel Jesús Niebla Gómez
collection DOAJ
description The neuroplasticity mechanisms of the organism form the basis of dissimilar therapies that seek to potentiate such effects to achieve relative improvement in a large number of neurodegenerative diseases. Included within this high number of conditions, Alzheimer's disease stands out, due to its direct relationship with the alarming figures of population aging in Cuba and the world. The objective of this bibliographic review was to describe the main therapeutic alternatives that are based on the neuroplasticity mechanism, applicable in patients with Alzheimer's disease. For this, a literature review was carried out, and relevant publications from the last five years were identified. It was concluded that, according to the strongest evidence found, the fundamental therapeutic alternatives are those focused on enhancing neuronal plasticity; standing out within this group of therapies, physical exercise, transcranial magnetic stimulation and increased concentrations of brain-derived neurotrophic factor. Especially notable the repetitive transcranial magnetic stimulation, due to its demonstrated ability to promote neuronal plasticity through different ways.
format Article
id doaj-art-c707c2300b684c9aadbe6d9e56f6c743
institution Kabale University
issn 1727-897X
language Spanish
publishDate 2020-08-01
publisher Centro Provincial de Información de Ciencias Médicas. Cienfuegos
record_format Article
series Medisur
spelling doaj-art-c707c2300b684c9aadbe6d9e56f6c7432025-01-30T21:28:56ZspaCentro Provincial de Información de Ciencias Médicas. CienfuegosMedisur1727-897X2020-08-011846756841872Neuroplasticity in Alzheimer's disease: a therapeutic alternative at the molecular levelNoel Jesús Niebla Gómez0Rodolfo Javier Rivero Morey1Víctor René Navarro Machado2Mariangel González León3Amanda Martínez Pérez4Universidad de Ciencias Médicas de Cienfuegos. CienfuegosUniversidad de Ciencias Médicas de Cienfuegos. CienfuegosUniversidad de Ciencias Médicas de Cienfuegos. CienfuegosUniversidad de Ciencias Médicas de Cienfuegos. CienfuegosUniversidad de Ciencias Médicas de Cienfuegos. CienfuegosThe neuroplasticity mechanisms of the organism form the basis of dissimilar therapies that seek to potentiate such effects to achieve relative improvement in a large number of neurodegenerative diseases. Included within this high number of conditions, Alzheimer's disease stands out, due to its direct relationship with the alarming figures of population aging in Cuba and the world. The objective of this bibliographic review was to describe the main therapeutic alternatives that are based on the neuroplasticity mechanism, applicable in patients with Alzheimer's disease. For this, a literature review was carried out, and relevant publications from the last five years were identified. It was concluded that, according to the strongest evidence found, the fundamental therapeutic alternatives are those focused on enhancing neuronal plasticity; standing out within this group of therapies, physical exercise, transcranial magnetic stimulation and increased concentrations of brain-derived neurotrophic factor. Especially notable the repetitive transcranial magnetic stimulation, due to its demonstrated ability to promote neuronal plasticity through different ways.http://medisur.sld.cu/index.php/medisur/article/view/4426plasticidad neuronalenfermedad de alzheimerrehabilitación neurológica
spellingShingle Noel Jesús Niebla Gómez
Rodolfo Javier Rivero Morey
Víctor René Navarro Machado
Mariangel González León
Amanda Martínez Pérez
Neuroplasticity in Alzheimer's disease: a therapeutic alternative at the molecular level
Medisur
plasticidad neuronal
enfermedad de alzheimer
rehabilitación neurológica
title Neuroplasticity in Alzheimer's disease: a therapeutic alternative at the molecular level
title_full Neuroplasticity in Alzheimer's disease: a therapeutic alternative at the molecular level
title_fullStr Neuroplasticity in Alzheimer's disease: a therapeutic alternative at the molecular level
title_full_unstemmed Neuroplasticity in Alzheimer's disease: a therapeutic alternative at the molecular level
title_short Neuroplasticity in Alzheimer's disease: a therapeutic alternative at the molecular level
title_sort neuroplasticity in alzheimer s disease a therapeutic alternative at the molecular level
topic plasticidad neuronal
enfermedad de alzheimer
rehabilitación neurológica
url http://medisur.sld.cu/index.php/medisur/article/view/4426
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AT victorrenenavarromachado neuroplasticityinalzheimersdiseaseatherapeuticalternativeatthemolecularlevel
AT mariangelgonzalezleon neuroplasticityinalzheimersdiseaseatherapeuticalternativeatthemolecularlevel
AT amandamartinezperez neuroplasticityinalzheimersdiseaseatherapeuticalternativeatthemolecularlevel