Testing an optimally weighted combination of common and/or rare variants with multiple traits.

Testing an optimally weighted combination of common and/or rare variants with multiple traits.

Recently, joint analysis of multiple traits has become popular because it can increase statistical power to identify genetic variants associated with complex diseases. In addition, there is increasing evidence indicating that pleiotropy is a widespread phenomenon in complex diseases. Currently, most...

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Bibliographic Details
Main Authors: Zhenchuan Wang, Qiuying Sha, Shurong Fang, Kui Zhang, Shuanglin Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0201186&type=printable
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