The feasibility of conducting non-pharmacological research studies in participants with mania: a grounded theory qualitative analysis of the Ottawa Sunglasses at Night study

Background Feasibility concerns around non-pharmacological interventions can be a barrier against clinical research in individuals with mania. Methods: As part of a randomized controlled trial using blue-blocking vs lightly-tinted glasses, we interviewed participants who were hospitalized with mania...

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Main Authors: Jessica Yu, Joseph K. Burns, Eric Mikhail, Marco Solmi, Simon Hatcher, Andrew L. Smith, Rébecca Robillard, Thanh Nguyen, Nicole Edgar, Tetyana Kendzerska, Mark Kaluzienski, Andrea Bardell, Jess G. Fiedorowicz
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:International Journal of Qualitative Studies on Health & Well-Being
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Online Access:http://dx.doi.org/10.1080/17482631.2025.2540795
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author Jessica Yu
Joseph K. Burns
Eric Mikhail
Marco Solmi
Simon Hatcher
Andrew L. Smith
Rébecca Robillard
Thanh Nguyen
Nicole Edgar
Tetyana Kendzerska
Mark Kaluzienski
Andrea Bardell
Jess G. Fiedorowicz
author_facet Jessica Yu
Joseph K. Burns
Eric Mikhail
Marco Solmi
Simon Hatcher
Andrew L. Smith
Rébecca Robillard
Thanh Nguyen
Nicole Edgar
Tetyana Kendzerska
Mark Kaluzienski
Andrea Bardell
Jess G. Fiedorowicz
author_sort Jessica Yu
collection DOAJ
description Background Feasibility concerns around non-pharmacological interventions can be a barrier against clinical research in individuals with mania. Methods: As part of a randomized controlled trial using blue-blocking vs lightly-tinted glasses, we interviewed participants who were hospitalized with mania and clinicians to gather insight on feasibility of recruitment and acceptability and implementation of tinted glasses according to the RE-AIM (Reach, Effectiveness, Adoption, Implementation and Maintenance) framework using a grounded theory approach. Semi-structured interviews with 24 participants and 10 clinicians were conducted. Results The central theory of “research readiness for a dark therapy trial” was developed from six main themes identified from participant interviews: motivation, patient-centred approach, benefits of participating, research understanding, efficacy of intervention and challenges. The central theory of “supportive of blue-blocking glasses” was developed from five themes identified from clinician interviews: importance and benefits of clinical research, clinician-patient interactions, acceptability of research for participants, documentation and challenges. Discussion This study identified themes from the experiences of participants and clinicians of the clinical trial that contribute to the feasibility and acceptability of blue-blocking glasses as an intervention for mania. The results of this qualitative study will inform implementation practices for clinical trials investigating non-pharmacological interventions for hospitalized individuals with mania and related acute psychiatric conditions which affect judgement.
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spelling doaj-art-c6f70c026017498e9443dd95dfe2cd8a2025-08-20T03:43:48ZengTaylor & Francis GroupInternational Journal of Qualitative Studies on Health & Well-Being1748-26231748-26312025-12-0120110.1080/17482631.2025.25407952540795The feasibility of conducting non-pharmacological research studies in participants with mania: a grounded theory qualitative analysis of the Ottawa Sunglasses at Night studyJessica Yu0Joseph K. Burns1Eric Mikhail2Marco Solmi3Simon Hatcher4Andrew L. Smith5Rébecca Robillard6Thanh Nguyen7Nicole Edgar8Tetyana Kendzerska9Mark Kaluzienski10Andrea Bardell11Jess G. Fiedorowicz12The Ottawa Hospital/Ottawa Hospital Research InstituteThe Ottawa Hospital/Ottawa Hospital Research InstituteThe Ottawa Hospital/Ottawa Hospital Research InstituteThe Ottawa Hospital/Ottawa Hospital Research InstituteThe Ottawa Hospital/Ottawa Hospital Research InstituteThe Ottawa Hospital/Ottawa Hospital Research InstituteUniversity of OttawaThe Ottawa Hospital/Ottawa Hospital Research InstituteThe Ottawa Hospital/Ottawa Hospital Research InstituteThe Ottawa Hospital/Ottawa Hospital Research InstituteThe Ottawa Hospital/Ottawa Hospital Research InstituteThe Ottawa Hospital/Ottawa Hospital Research InstituteThe Ottawa Hospital/Ottawa Hospital Research InstituteBackground Feasibility concerns around non-pharmacological interventions can be a barrier against clinical research in individuals with mania. Methods: As part of a randomized controlled trial using blue-blocking vs lightly-tinted glasses, we interviewed participants who were hospitalized with mania and clinicians to gather insight on feasibility of recruitment and acceptability and implementation of tinted glasses according to the RE-AIM (Reach, Effectiveness, Adoption, Implementation and Maintenance) framework using a grounded theory approach. Semi-structured interviews with 24 participants and 10 clinicians were conducted. Results The central theory of “research readiness for a dark therapy trial” was developed from six main themes identified from participant interviews: motivation, patient-centred approach, benefits of participating, research understanding, efficacy of intervention and challenges. The central theory of “supportive of blue-blocking glasses” was developed from five themes identified from clinician interviews: importance and benefits of clinical research, clinician-patient interactions, acceptability of research for participants, documentation and challenges. Discussion This study identified themes from the experiences of participants and clinicians of the clinical trial that contribute to the feasibility and acceptability of blue-blocking glasses as an intervention for mania. The results of this qualitative study will inform implementation practices for clinical trials investigating non-pharmacological interventions for hospitalized individuals with mania and related acute psychiatric conditions which affect judgement.http://dx.doi.org/10.1080/17482631.2025.2540795bipolar disorderblue-blocking-glassesdark therapymaniaqualitative studygrounded theory
spellingShingle Jessica Yu
Joseph K. Burns
Eric Mikhail
Marco Solmi
Simon Hatcher
Andrew L. Smith
Rébecca Robillard
Thanh Nguyen
Nicole Edgar
Tetyana Kendzerska
Mark Kaluzienski
Andrea Bardell
Jess G. Fiedorowicz
The feasibility of conducting non-pharmacological research studies in participants with mania: a grounded theory qualitative analysis of the Ottawa Sunglasses at Night study
International Journal of Qualitative Studies on Health & Well-Being
bipolar disorder
blue-blocking-glasses
dark therapy
mania
qualitative study
grounded theory
title The feasibility of conducting non-pharmacological research studies in participants with mania: a grounded theory qualitative analysis of the Ottawa Sunglasses at Night study
title_full The feasibility of conducting non-pharmacological research studies in participants with mania: a grounded theory qualitative analysis of the Ottawa Sunglasses at Night study
title_fullStr The feasibility of conducting non-pharmacological research studies in participants with mania: a grounded theory qualitative analysis of the Ottawa Sunglasses at Night study
title_full_unstemmed The feasibility of conducting non-pharmacological research studies in participants with mania: a grounded theory qualitative analysis of the Ottawa Sunglasses at Night study
title_short The feasibility of conducting non-pharmacological research studies in participants with mania: a grounded theory qualitative analysis of the Ottawa Sunglasses at Night study
title_sort feasibility of conducting non pharmacological research studies in participants with mania a grounded theory qualitative analysis of the ottawa sunglasses at night study
topic bipolar disorder
blue-blocking-glasses
dark therapy
mania
qualitative study
grounded theory
url http://dx.doi.org/10.1080/17482631.2025.2540795
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