Diagnosis progress of carcinoma of unknown primary

Carcinoma of unknown primary (CUP) is a common and complex type of tumor in clinical practice, where the primary site cannot be determined through conventional diagnostic methods, posing significant challenges for clinical diagnosis and treatment. In recent years, advancements in gene expression pro...

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Main Authors: Yun Qiao, Mei Wang, Kaiyuan Hui, Xiaodong Jiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-11-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2024.1510443/full
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author Yun Qiao
Yun Qiao
Mei Wang
Kaiyuan Hui
Xiaodong Jiang
Xiaodong Jiang
author_facet Yun Qiao
Yun Qiao
Mei Wang
Kaiyuan Hui
Xiaodong Jiang
Xiaodong Jiang
author_sort Yun Qiao
collection DOAJ
description Carcinoma of unknown primary (CUP) is a common and complex type of tumor in clinical practice, where the primary site cannot be determined through conventional diagnostic methods, posing significant challenges for clinical diagnosis and treatment. In recent years, advancements in gene expression profiling and genetic testing technologies have provided new perspectives for CUP research, driving progress in this field. By analyzing gene expression profiles, researchers can more effectively identify the tissue origin of tumors, thereby improving diagnostic accuracy. At the same time, the potential application of genetic testing is continuously being explored, offering new possibilities for personalized treatment. This article aims to discuss the latest advancements in the diagnosis of CUP, analyze the importance of gene expression profiling and genetic testing in tumor origin identification and their clinical applications, and summarize current research progress and future research directions, with the goal of providing a theoretical basis for the early diagnosis and treatment of CUP.
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publishDate 2024-11-01
publisher Frontiers Media S.A.
record_format Article
series Frontiers in Oncology
spelling doaj-art-c6eec1bed37b4f9eb30b55b24fd489382025-08-20T02:23:08ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2024-11-011410.3389/fonc.2024.15104431510443Diagnosis progress of carcinoma of unknown primaryYun Qiao0Yun Qiao1Mei Wang2Kaiyuan Hui3Xiaodong Jiang4Xiaodong Jiang5Department of Oncology, Lianyungang Clinical College of Nanjing Medical University, Lianyungang, ChinaDepartment of Oncology, The Affiliated Lianyungang Hospital of Xuzhou Medical University, Lianyungang, ChinaDepartment of Oncology, The Affiliated Lianyungang Hospital of Xuzhou Medical University, Lianyungang, ChinaDepartment of Oncology, The Affiliated Lianyungang Hospital of Xuzhou Medical University, Lianyungang, ChinaDepartment of Oncology, Lianyungang Clinical College of Nanjing Medical University, Lianyungang, ChinaDepartment of Oncology, The Affiliated Lianyungang Hospital of Xuzhou Medical University, Lianyungang, ChinaCarcinoma of unknown primary (CUP) is a common and complex type of tumor in clinical practice, where the primary site cannot be determined through conventional diagnostic methods, posing significant challenges for clinical diagnosis and treatment. In recent years, advancements in gene expression profiling and genetic testing technologies have provided new perspectives for CUP research, driving progress in this field. By analyzing gene expression profiles, researchers can more effectively identify the tissue origin of tumors, thereby improving diagnostic accuracy. At the same time, the potential application of genetic testing is continuously being explored, offering new possibilities for personalized treatment. This article aims to discuss the latest advancements in the diagnosis of CUP, analyze the importance of gene expression profiling and genetic testing in tumor origin identification and their clinical applications, and summarize current research progress and future research directions, with the goal of providing a theoretical basis for the early diagnosis and treatment of CUP.https://www.frontiersin.org/articles/10.3389/fonc.2024.1510443/fullcarcinoma of unknown primarygene expression profilinggenetic testingpersonalized treatmenttraceable diagnosis
spellingShingle Yun Qiao
Yun Qiao
Mei Wang
Kaiyuan Hui
Xiaodong Jiang
Xiaodong Jiang
Diagnosis progress of carcinoma of unknown primary
Frontiers in Oncology
carcinoma of unknown primary
gene expression profiling
genetic testing
personalized treatment
traceable diagnosis
title Diagnosis progress of carcinoma of unknown primary
title_full Diagnosis progress of carcinoma of unknown primary
title_fullStr Diagnosis progress of carcinoma of unknown primary
title_full_unstemmed Diagnosis progress of carcinoma of unknown primary
title_short Diagnosis progress of carcinoma of unknown primary
title_sort diagnosis progress of carcinoma of unknown primary
topic carcinoma of unknown primary
gene expression profiling
genetic testing
personalized treatment
traceable diagnosis
url https://www.frontiersin.org/articles/10.3389/fonc.2024.1510443/full
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