Previous Leisure-Time Physical Activity Dose Dependently Decreases Ischemic Stroke Severity
In the present subanalysis of a cross-sectional study showing the favorable effect of prior transient ischemia, leisure-time physical activity, and lipid-lowering drug therapy on stroke severity, we aimed to evaluate whether previous physical activity was dose dependently associated to minor stroke...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Stroke Research and Treatment |
| Online Access: | http://dx.doi.org/10.1155/2012/614925 |
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| _version_ | 1849684102110773248 |
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| author | Dominique Deplanque Isabelle Masse Christian Libersa Didier Leys Régis Bordet |
| author_facet | Dominique Deplanque Isabelle Masse Christian Libersa Didier Leys Régis Bordet |
| author_sort | Dominique Deplanque |
| collection | DOAJ |
| description | In the present subanalysis of a cross-sectional study showing the favorable effect of prior transient ischemia, leisure-time physical activity, and lipid-lowering drug therapy on stroke severity, we aimed to evaluate whether previous physical activity was dose dependently associated to minor stroke (NIHSS 0–3) and to identify possible underlying factors. Among 362 consecutive patients, less severe stroke was related to weekly exercise duration prior to stroke (no exercise: 36.1%; <2 hours: 49.3%; 2–5 hours: 58.8%; >5 hours: 64.0%; 𝑃=0.003). Only weak and moderate exercise practices were protective (weak: 50.0%; moderate: 79.3%; heavy: 22.2%; 𝑃<0.0001). Such a beneficial effect was observed independently of age and was associated with a trend to a lower frequency of arterial hypertension, alcohol abuse, and a better metabolic profile. Besides other therapeutic approaches, physical activity may be a simple way to decrease cerebral ischemia severity. |
| format | Article |
| id | doaj-art-c6ddfe1b95854c4e81af313f44b38ab3 |
| institution | DOAJ |
| issn | 2090-8105 2042-0056 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Stroke Research and Treatment |
| spelling | doaj-art-c6ddfe1b95854c4e81af313f44b38ab32025-08-20T03:23:34ZengWileyStroke Research and Treatment2090-81052042-00562012-01-01201210.1155/2012/614925614925Previous Leisure-Time Physical Activity Dose Dependently Decreases Ischemic Stroke SeverityDominique Deplanque0Isabelle Masse1Christian Libersa2Didier Leys3Régis Bordet4Department of Medical Pharmacology, Faculty of Medicine, University Lille-North of France, 1 Place Verdun, 59045 Lille, FranceDepartment of Medical Pharmacology, Faculty of Medicine, University Lille-North of France, 1 Place Verdun, 59045 Lille, FranceDepartment of Medical Pharmacology, Faculty of Medicine, University Lille-North of France, 1 Place Verdun, 59045 Lille, FranceNeurology Department and Stroke Unit, University Lille-North of France, Lille University Hospital, 59037 Lille, FranceDepartment of Medical Pharmacology, Faculty of Medicine, University Lille-North of France, 1 Place Verdun, 59045 Lille, FranceIn the present subanalysis of a cross-sectional study showing the favorable effect of prior transient ischemia, leisure-time physical activity, and lipid-lowering drug therapy on stroke severity, we aimed to evaluate whether previous physical activity was dose dependently associated to minor stroke (NIHSS 0–3) and to identify possible underlying factors. Among 362 consecutive patients, less severe stroke was related to weekly exercise duration prior to stroke (no exercise: 36.1%; <2 hours: 49.3%; 2–5 hours: 58.8%; >5 hours: 64.0%; 𝑃=0.003). Only weak and moderate exercise practices were protective (weak: 50.0%; moderate: 79.3%; heavy: 22.2%; 𝑃<0.0001). Such a beneficial effect was observed independently of age and was associated with a trend to a lower frequency of arterial hypertension, alcohol abuse, and a better metabolic profile. Besides other therapeutic approaches, physical activity may be a simple way to decrease cerebral ischemia severity.http://dx.doi.org/10.1155/2012/614925 |
| spellingShingle | Dominique Deplanque Isabelle Masse Christian Libersa Didier Leys Régis Bordet Previous Leisure-Time Physical Activity Dose Dependently Decreases Ischemic Stroke Severity Stroke Research and Treatment |
| title | Previous Leisure-Time Physical Activity Dose Dependently Decreases Ischemic Stroke Severity |
| title_full | Previous Leisure-Time Physical Activity Dose Dependently Decreases Ischemic Stroke Severity |
| title_fullStr | Previous Leisure-Time Physical Activity Dose Dependently Decreases Ischemic Stroke Severity |
| title_full_unstemmed | Previous Leisure-Time Physical Activity Dose Dependently Decreases Ischemic Stroke Severity |
| title_short | Previous Leisure-Time Physical Activity Dose Dependently Decreases Ischemic Stroke Severity |
| title_sort | previous leisure time physical activity dose dependently decreases ischemic stroke severity |
| url | http://dx.doi.org/10.1155/2012/614925 |
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