Dysfunctional tetraspanin 7 (TSP‐7) in Caenorhabditis elegans promotes; increases in average life‐ & health‐span, stress‐induced survival and motility
Caenorhabditis elegans (C. elegans) tetraspanin‐7 (TSP‐7) protein is an orthologue of the Human tetraspanin CD63, which has recently been shown to be a negative regulator of autophagy. In this study a mutant strain of wild‐type (WT) C. elegans (tm5761) with a 352 bp deletion in the tsp‐7 gene, was s...
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| Main Authors: | Brogan Jones, Laurence Seabra, Francesco Michelangeli |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2025-06-01
|
| Series: | FEBS Open Bio |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/2211-5463.70013 |
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