Serum phospholipids and sphingolipids are linked to early-stage osteoarthritis by lipidomic profiling

Serum phospholipids and sphingolipids are linked to early-stage osteoarthritis by lipidomic profiling

Abstract Background Osteoarthritis (OA) is associated with abnormal lipid metabolism, wherein elevated levels of phospholipids (PLs) and sphingolipids (SLs) in human and canine synovial fluid (SF) have been observed. The aim of this lipidomic study was to evaluate how closely blood lipid levels refl...

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Bibliographic Details
Main Authors: Gerrit Eichner, Gerhard Liebisch, Christiane Hild, Markus Rickert, Juergen Steinmeyer
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Arthritis Research & Therapy
Subjects:
Phospholipids
Sphingolipids
Osteoarthritis
Serum
Synovial fluid
Lipidomic
Online Access:https://doi.org/10.1186/s13075-025-03537-4
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