Clinical Profiles of Patients with Keratoconus Visiting a Tertiary Eye Center in Kuala Lumpur, Malaysia

Purpose: To evaluate the demography, clinical characteristics, and risk factors of keratoconus (KCN) patients attending a tertiary eye center in Kuala Lumpur, Malaysia. Methods: This prospective cross-sectional study included KCN patients who visited Ophthalmology Clinic, Hospital Canselor Tuanku Mu...

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Main Authors: Norsyariza Razak, Bariah Mohd Ali, Wan Haslina Wan Abdul Halim
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-07-01
Series:Journal of Current Ophthalmology
Subjects:
Online Access:https://journals.lww.com/10.4103/joco.joco_75_24
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author Norsyariza Razak
Bariah Mohd Ali
Wan Haslina Wan Abdul Halim
author_facet Norsyariza Razak
Bariah Mohd Ali
Wan Haslina Wan Abdul Halim
author_sort Norsyariza Razak
collection DOAJ
description Purpose: To evaluate the demography, clinical characteristics, and risk factors of keratoconus (KCN) patients attending a tertiary eye center in Kuala Lumpur, Malaysia. Methods: This prospective cross-sectional study included KCN patients who visited Ophthalmology Clinic, Hospital Canselor Tuanku Muhriz UKM, Kuala Lumpur, Malaysia between January 2022 and October 2023. Their demographic details, best-corrected visual acuity (BCVA), clinical findings, refraction, and risk factors were recorded. Topographical data and KCN classification were obtained through Oculus Pentacam (Wetzlar, Germany). Results: Out of 71,862 cases, 78 KCN patients were identified, with the majority having bilateral KCN (75.6%). The patients were 27.90 ± 7.37 years old on average and were predominantly male (55.1%) and Malay (70.5%). The KCN severity also varied between patients (12.8% mild, 43.6% moderate, and 43.6% severe). No significant association was found between the patient’s demographics and KCN severity (P > 0.05). The patients had a mean BCVA of 0.39 ± 0.48 and a mean spherical equivalent of −5.30 ± 4.45. Eye rubbing (85.9%) and atopy (80.77%) were identified as the most common risk factors for KCN, contrary to family history (12.8%). Meanwhile, Scissors Movement, Vogt Striae, and Munson’s Sign were among the highest percentages of clinical findings presented. Furthermore, 68.7% of KCN cases also reported ocular allergies (papillae). Conclusion: Patients’ demographics were not a determinant of KCN severity. Eye rubbing and atopy were the most significant risk factors for KCN in Malaysia. Thus, KCN screening for patients with atopy and ocular allergies is vital for KCN prevention.
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spelling doaj-art-c6d427f8092e4bbd9a63d17e9ac9a2c22025-08-20T03:31:40ZengWolters Kluwer Medknow PublicationsJournal of Current Ophthalmology2452-23252024-07-0136325225710.4103/joco.joco_75_24Clinical Profiles of Patients with Keratoconus Visiting a Tertiary Eye Center in Kuala Lumpur, MalaysiaNorsyariza RazakBariah Mohd AliWan Haslina Wan Abdul HalimPurpose: To evaluate the demography, clinical characteristics, and risk factors of keratoconus (KCN) patients attending a tertiary eye center in Kuala Lumpur, Malaysia. Methods: This prospective cross-sectional study included KCN patients who visited Ophthalmology Clinic, Hospital Canselor Tuanku Muhriz UKM, Kuala Lumpur, Malaysia between January 2022 and October 2023. Their demographic details, best-corrected visual acuity (BCVA), clinical findings, refraction, and risk factors were recorded. Topographical data and KCN classification were obtained through Oculus Pentacam (Wetzlar, Germany). Results: Out of 71,862 cases, 78 KCN patients were identified, with the majority having bilateral KCN (75.6%). The patients were 27.90 ± 7.37 years old on average and were predominantly male (55.1%) and Malay (70.5%). The KCN severity also varied between patients (12.8% mild, 43.6% moderate, and 43.6% severe). No significant association was found between the patient’s demographics and KCN severity (P > 0.05). The patients had a mean BCVA of 0.39 ± 0.48 and a mean spherical equivalent of −5.30 ± 4.45. Eye rubbing (85.9%) and atopy (80.77%) were identified as the most common risk factors for KCN, contrary to family history (12.8%). Meanwhile, Scissors Movement, Vogt Striae, and Munson’s Sign were among the highest percentages of clinical findings presented. Furthermore, 68.7% of KCN cases also reported ocular allergies (papillae). Conclusion: Patients’ demographics were not a determinant of KCN severity. Eye rubbing and atopy were the most significant risk factors for KCN in Malaysia. Thus, KCN screening for patients with atopy and ocular allergies is vital for KCN prevention.https://journals.lww.com/10.4103/joco.joco_75_24clinical characteristicdemographickeratoconusrisk factor
spellingShingle Norsyariza Razak
Bariah Mohd Ali
Wan Haslina Wan Abdul Halim
Clinical Profiles of Patients with Keratoconus Visiting a Tertiary Eye Center in Kuala Lumpur, Malaysia
Journal of Current Ophthalmology
clinical characteristic
demographic
keratoconus
risk factor
title Clinical Profiles of Patients with Keratoconus Visiting a Tertiary Eye Center in Kuala Lumpur, Malaysia
title_full Clinical Profiles of Patients with Keratoconus Visiting a Tertiary Eye Center in Kuala Lumpur, Malaysia
title_fullStr Clinical Profiles of Patients with Keratoconus Visiting a Tertiary Eye Center in Kuala Lumpur, Malaysia
title_full_unstemmed Clinical Profiles of Patients with Keratoconus Visiting a Tertiary Eye Center in Kuala Lumpur, Malaysia
title_short Clinical Profiles of Patients with Keratoconus Visiting a Tertiary Eye Center in Kuala Lumpur, Malaysia
title_sort clinical profiles of patients with keratoconus visiting a tertiary eye center in kuala lumpur malaysia
topic clinical characteristic
demographic
keratoconus
risk factor
url https://journals.lww.com/10.4103/joco.joco_75_24
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