A Case of Adult-onset Still's Disease Presented with Fever and Neutrophil-dominant Pleural Effusion
We report a case of adult-onset Still's disease (AOSD) presenting with fever, myalgia, and pleural effusion. The patient exhibited significantly elevated inflammatory markers and exudative pleural effusion with markedly elevated leukocyte count showing neutrophilic predominance. After comprehen...
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Editorial Office of Medical Journal of Peking Union Medical College Hospital
2025-01-01
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| Series: | Xiehe Yixue Zazhi |
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| Online Access: | https://xhyxzz.pumch.cn/article/doi/10.12290/xhyxzz.2024-0983 |
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| author | NIU Chao MAI YuLin LI HanXue QIAN JunYan CAO Wei |
| author_facet | NIU Chao MAI YuLin LI HanXue QIAN JunYan CAO Wei |
| author_sort | NIU Chao |
| collection | DOAJ |
| description | We report a case of adult-onset Still's disease (AOSD) presenting with fever, myalgia, and pleural effusion. The patient exhibited significantly elevated inflammatory markers and exudative pleural effusion with markedly elevated leukocyte count showing neutrophilic predominance. After comprehensive exclusion of infectious etiologies, the diagnosis of AOSD was established. Clinical symptoms resolved following anti-inflammatory therapy with glucocorticoids and tocilizumab. This case highlights a critical clinical insight: while infection is a common cause of elevated inflammatory markers, it is not an invariable etiology. In such presentations, meticulous clinical observation, thorough diagnostic screening, and systematic inference are essential for accurate diagnosis. |
| format | Article |
| id | doaj-art-c6d3e6541bbb413c9d5b9befed59ce9d |
| institution | DOAJ |
| issn | 1674-9081 |
| language | zho |
| publishDate | 2025-01-01 |
| publisher | Editorial Office of Medical Journal of Peking Union Medical College Hospital |
| record_format | Article |
| series | Xiehe Yixue Zazhi |
| spelling | doaj-art-c6d3e6541bbb413c9d5b9befed59ce9d2025-08-20T02:58:21ZzhoEditorial Office of Medical Journal of Peking Union Medical College HospitalXiehe Yixue Zazhi1674-90812025-01-011641057106110.12290/xhyxzz.2024-0983A Case of Adult-onset Still's Disease Presented with Fever and Neutrophil-dominant Pleural EffusionNIU ChaoMAI YuLin0LI HanXue1QIAN JunYan2CAO Wei3Department of Infectious Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, ChinaDepartment of Immunology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, ChinaDepartment of Immunology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, ChinaDepartment of Infectious Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, ChinaWe report a case of adult-onset Still's disease (AOSD) presenting with fever, myalgia, and pleural effusion. The patient exhibited significantly elevated inflammatory markers and exudative pleural effusion with markedly elevated leukocyte count showing neutrophilic predominance. After comprehensive exclusion of infectious etiologies, the diagnosis of AOSD was established. Clinical symptoms resolved following anti-inflammatory therapy with glucocorticoids and tocilizumab. This case highlights a critical clinical insight: while infection is a common cause of elevated inflammatory markers, it is not an invariable etiology. In such presentations, meticulous clinical observation, thorough diagnostic screening, and systematic inference are essential for accurate diagnosis.https://xhyxzz.pumch.cn/article/doi/10.12290/xhyxzz.2024-0983pleural effusionexudativeadult-onset still's diseaseinflammation |
| spellingShingle | NIU Chao MAI YuLin LI HanXue QIAN JunYan CAO Wei A Case of Adult-onset Still's Disease Presented with Fever and Neutrophil-dominant Pleural Effusion Xiehe Yixue Zazhi pleural effusion exudative adult-onset still's disease inflammation |
| title | A Case of Adult-onset Still's Disease Presented with Fever and Neutrophil-dominant Pleural Effusion |
| title_full | A Case of Adult-onset Still's Disease Presented with Fever and Neutrophil-dominant Pleural Effusion |
| title_fullStr | A Case of Adult-onset Still's Disease Presented with Fever and Neutrophil-dominant Pleural Effusion |
| title_full_unstemmed | A Case of Adult-onset Still's Disease Presented with Fever and Neutrophil-dominant Pleural Effusion |
| title_short | A Case of Adult-onset Still's Disease Presented with Fever and Neutrophil-dominant Pleural Effusion |
| title_sort | case of adult onset still s disease presented with fever and neutrophil dominant pleural effusion |
| topic | pleural effusion exudative adult-onset still's disease inflammation |
| url | https://xhyxzz.pumch.cn/article/doi/10.12290/xhyxzz.2024-0983 |
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