Paracetamol-induced hepatotoxicity in a malnourished patient: A case report
Acetaminophen, an analgesic and antipyretic with a favorable safety profile, is used globally. However, excessive doses can lead to severe hepatotoxicity and acute liver failure. We present a case report that describes the unfortunate demise of a 48-year-old male patient with colon carcinoma who dev...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2024-04-01
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| Series: | MGM Journal of Medical Sciences |
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| Online Access: | https://doi.org/10.4103/mgmj.mgmj_88_24 |
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| author | Sudhanshu Shukla Tejashree Sridhar Jayasheela Siddalingayya Hiremath Sanathkumar B. Nyamagoud Viswanatha Agadi Hiremath Swamy |
| author_facet | Sudhanshu Shukla Tejashree Sridhar Jayasheela Siddalingayya Hiremath Sanathkumar B. Nyamagoud Viswanatha Agadi Hiremath Swamy |
| author_sort | Sudhanshu Shukla |
| collection | DOAJ |
| description | Acetaminophen, an analgesic and antipyretic with a favorable safety profile, is used globally. However, excessive doses can lead to severe hepatotoxicity and acute liver failure. We present a case report that describes the unfortunate demise of a 48-year-old male patient with colon carcinoma who developed severe hepatotoxicity attributed to the administration of paracetamol following right radical hemicolectomy. Despite the patient receiving paracetamol at a dosage below the recommended limit under medical supervision, he experienced a rapid deterioration in liver function, leading to a cascade of life-threatening complications. The intricate interplay between medication administration and patient-specific factors emphasizes the ongoing need for the medical community to evolve and optimize treatment strategies for improved patient outcomes. |
| format | Article |
| id | doaj-art-c6d2575eacf242e99f5a550990a599dd |
| institution | Kabale University |
| issn | 2347-7946 2347-7962 |
| language | English |
| publishDate | 2024-04-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | MGM Journal of Medical Sciences |
| spelling | doaj-art-c6d2575eacf242e99f5a550990a599dd2025-01-25T10:19:23ZengWolters Kluwer Medknow PublicationsMGM Journal of Medical Sciences2347-79462347-79622024-04-0111237938210.4103/mgmj.mgmj_88_24Paracetamol-induced hepatotoxicity in a malnourished patient: A case reportSudhanshu ShuklaTejashree SridharJayasheela Siddalingayya HiremathSanathkumar B. NyamagoudViswanatha Agadi Hiremath SwamyAcetaminophen, an analgesic and antipyretic with a favorable safety profile, is used globally. However, excessive doses can lead to severe hepatotoxicity and acute liver failure. We present a case report that describes the unfortunate demise of a 48-year-old male patient with colon carcinoma who developed severe hepatotoxicity attributed to the administration of paracetamol following right radical hemicolectomy. Despite the patient receiving paracetamol at a dosage below the recommended limit under medical supervision, he experienced a rapid deterioration in liver function, leading to a cascade of life-threatening complications. The intricate interplay between medication administration and patient-specific factors emphasizes the ongoing need for the medical community to evolve and optimize treatment strategies for improved patient outcomes.https://doi.org/10.4103/mgmj.mgmj_88_24acetaminophenhepatic encephalopathyliver failuremalnutrition |
| spellingShingle | Sudhanshu Shukla Tejashree Sridhar Jayasheela Siddalingayya Hiremath Sanathkumar B. Nyamagoud Viswanatha Agadi Hiremath Swamy Paracetamol-induced hepatotoxicity in a malnourished patient: A case report MGM Journal of Medical Sciences acetaminophen hepatic encephalopathy liver failure malnutrition |
| title | Paracetamol-induced hepatotoxicity in a malnourished patient: A case report |
| title_full | Paracetamol-induced hepatotoxicity in a malnourished patient: A case report |
| title_fullStr | Paracetamol-induced hepatotoxicity in a malnourished patient: A case report |
| title_full_unstemmed | Paracetamol-induced hepatotoxicity in a malnourished patient: A case report |
| title_short | Paracetamol-induced hepatotoxicity in a malnourished patient: A case report |
| title_sort | paracetamol induced hepatotoxicity in a malnourished patient a case report |
| topic | acetaminophen hepatic encephalopathy liver failure malnutrition |
| url | https://doi.org/10.4103/mgmj.mgmj_88_24 |
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