The effect of age on the intestinal mucus thickness, microbiota composition and immunity in relation to sex in mice.

A mucus layer covers and protects the intestinal epithelial cells from direct contact with microbes. This mucus layer not only prevents inflammation but also plays an essential role in microbiota colonization, indicating the complex interplay between mucus composition-microbiota and intestinal healt...

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Main Authors: Marlies Elderman, Bruno Sovran, Floor Hugenholtz, Katrine Graversen, Myrte Huijskes, Eva Houtsma, Clara Belzer, Mark Boekschoten, Paul de Vos, Jan Dekker, Jerry Wells, Marijke Faas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0184274&type=printable
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