Clinical laboratory characteristic of hospitalized patients with HBsAg negative chronic hepatitis B
One of the phases of the natural course of chronic hepatitis В is «HBsAg negative» phase, the clinical and prognostic significance of which is not defined yet. The frequency of HBsAg negative phase of chronic hepatitis В among the hospitalized patients of Clinical Infectious Diseases Hospital named...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
Journal Infectology
2014-09-01
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| Series: | Журнал инфектологии |
| Subjects: | |
| Online Access: | https://journal.niidi.ru/jofin/article/view/238 |
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| Summary: | One of the phases of the natural course of chronic hepatitis В is «HBsAg negative» phase, the clinical and prognostic significance of which is not defined yet. The frequency of HBsAg negative phase of chronic hepatitis В among the hospitalized patients of Clinical Infectious Diseases Hospital named by S.P. Botkin (Saint-Petersburg), for the period of 2010–2012 was assessed in this study. We analyzed the age structure of the patients, their clinical-laboratory inde[es and set the frequency of cirrhotic stage of disease. The «HBsAg negative» phase is revealed among quarter of patients with chronic hepatitis В the middle aged group (45–59 years old). The 84 (67,2%) hospitalized patients with HBsAg negative chronic hepatitis В diagnosed were given a diagnosis of cirrhotic stage disease. Thus, the spontaneous clearance of HBsAg from blood serum is not always the evidence of the prognostically favorable course of chronic hepatitis B. |
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| ISSN: | 2072-6732 |