Antimicrobial Activity of Thin Solid Films of Silver Doped Hydroxyapatite Prepared by Sol-Gel Method

In this work, the preparation and characterization of silver doped hydroxyapatite thin films were reported and their antimicrobial activity was characterized. Silver doped hydroxyapatite (Ag:HAp) thin films coatings substrate was prepared on commercially pure Si disks by sol-gel method. The silver d...

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Main Authors: Simona Liliana Iconaru, Patrick Chapon, Philippe Le Coustumer, Daniela Predoi
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1155/2014/165351
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author Simona Liliana Iconaru
Patrick Chapon
Philippe Le Coustumer
Daniela Predoi
author_facet Simona Liliana Iconaru
Patrick Chapon
Philippe Le Coustumer
Daniela Predoi
author_sort Simona Liliana Iconaru
collection DOAJ
description In this work, the preparation and characterization of silver doped hydroxyapatite thin films were reported and their antimicrobial activity was characterized. Silver doped hydroxyapatite (Ag:HAp) thin films coatings substrate was prepared on commercially pure Si disks by sol-gel method. The silver doped hydroxyapatite thin films were characterized by various techniques such as Scanning electron microscopy (SEM) with energy Dispersive X-ray attachment (X-EDS), Fourier transform infrared spectroscopy (FT-IR), and glow discharge optical emission spectroscopy (GDOES). These techniques have permitted the structural and chemical characterisation of the silver doped hydroxyapatite thin films. The antimicrobial effect of the Ag:HAp thin films on Escherichia coli and Staphylococcus aureus bacteria was then investigated. This is the first study on the antimicrobial effect of Ag:HAp thin films obtained by sol-gel method. The results of this study have shown that the Ag:HAp thin films with xAg=0.5 are effective against E. coli and S. aureus after 24 h.
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institution Kabale University
issn 2356-6140
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publishDate 2014-01-01
publisher Wiley
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spelling doaj-art-c6a5d34d986446138263011ec8f1932f2025-02-03T01:30:54ZengWileyThe Scientific World Journal2356-61401537-744X2014-01-01201410.1155/2014/165351165351Antimicrobial Activity of Thin Solid Films of Silver Doped Hydroxyapatite Prepared by Sol-Gel MethodSimona Liliana Iconaru0Patrick Chapon1Philippe Le Coustumer2Daniela Predoi3National Institute of Materials Physics, P.O. Box MG 07, Magurele, RomaniaHoriba Jobin Yvon S.A., 16-18 rue du Canal, 91165 Longjumeau Cedex, FranceUniversite Bordeaux, EA 4592 Géoressources & Environnement, ENSEGID, 1 allée F. Daguin, 33607 Pessac Cedex, FranceNational Institute of Materials Physics, P.O. Box MG 07, Magurele, RomaniaIn this work, the preparation and characterization of silver doped hydroxyapatite thin films were reported and their antimicrobial activity was characterized. Silver doped hydroxyapatite (Ag:HAp) thin films coatings substrate was prepared on commercially pure Si disks by sol-gel method. The silver doped hydroxyapatite thin films were characterized by various techniques such as Scanning electron microscopy (SEM) with energy Dispersive X-ray attachment (X-EDS), Fourier transform infrared spectroscopy (FT-IR), and glow discharge optical emission spectroscopy (GDOES). These techniques have permitted the structural and chemical characterisation of the silver doped hydroxyapatite thin films. The antimicrobial effect of the Ag:HAp thin films on Escherichia coli and Staphylococcus aureus bacteria was then investigated. This is the first study on the antimicrobial effect of Ag:HAp thin films obtained by sol-gel method. The results of this study have shown that the Ag:HAp thin films with xAg=0.5 are effective against E. coli and S. aureus after 24 h.http://dx.doi.org/10.1155/2014/165351
spellingShingle Simona Liliana Iconaru
Patrick Chapon
Philippe Le Coustumer
Daniela Predoi
Antimicrobial Activity of Thin Solid Films of Silver Doped Hydroxyapatite Prepared by Sol-Gel Method
The Scientific World Journal
title Antimicrobial Activity of Thin Solid Films of Silver Doped Hydroxyapatite Prepared by Sol-Gel Method
title_full Antimicrobial Activity of Thin Solid Films of Silver Doped Hydroxyapatite Prepared by Sol-Gel Method
title_fullStr Antimicrobial Activity of Thin Solid Films of Silver Doped Hydroxyapatite Prepared by Sol-Gel Method
title_full_unstemmed Antimicrobial Activity of Thin Solid Films of Silver Doped Hydroxyapatite Prepared by Sol-Gel Method
title_short Antimicrobial Activity of Thin Solid Films of Silver Doped Hydroxyapatite Prepared by Sol-Gel Method
title_sort antimicrobial activity of thin solid films of silver doped hydroxyapatite prepared by sol gel method
url http://dx.doi.org/10.1155/2014/165351
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AT patrickchapon antimicrobialactivityofthinsolidfilmsofsilverdopedhydroxyapatitepreparedbysolgelmethod
AT philippelecoustumer antimicrobialactivityofthinsolidfilmsofsilverdopedhydroxyapatitepreparedbysolgelmethod
AT danielapredoi antimicrobialactivityofthinsolidfilmsofsilverdopedhydroxyapatitepreparedbysolgelmethod