Antioxidant status of one-year-old carp infected with Eudiplozoon nipponicum and the effects of corrective factors

One of the least studied monogeneosis diseases to date is carp diplostomosis. Outbreaks of this disease have been increasingly reported in fish farms in the western region of Ukraine. Moreover, this parasite is most commonly found in larger quantities in young fish. The aim of this study was to inve...

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Main Authors: O. V. Fedorovych, B. B. Saiuk, B. V. Gutyj, M. P. Drach, T. V. Martyshuk, S. I. Kravets, A. O. Boiko, U. M. Vus, O. Ye. Vozna, Kh. Ya. Leskiv, V. Ya. Momut
Format: Article
Language:English
Published: Stepan Gzhytskyi National University of Veterinary Medicine and Biotechnologies Lviv 2024-09-01
Series:Науковий вісник Львівського національного університету ветеринарної медицини та біотехнологій імені С.З. Гжицького. Серія: Сільськогосподарські науки
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Online Access:https://nvlvet.com.ua/index.php/agriculture/article/view/5413
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author O. V. Fedorovych
B. B. Saiuk
B. V. Gutyj
M. P. Drach
T. V. Martyshuk
S. I. Kravets
A. O. Boiko
U. M. Vus
O. Ye. Vozna
Kh. Ya. Leskiv
V. Ya. Momut
author_facet O. V. Fedorovych
B. B. Saiuk
B. V. Gutyj
M. P. Drach
T. V. Martyshuk
S. I. Kravets
A. O. Boiko
U. M. Vus
O. Ye. Vozna
Kh. Ya. Leskiv
V. Ya. Momut
author_sort O. V. Fedorovych
collection DOAJ
description One of the least studied monogeneosis diseases to date is carp diplostomosis. Outbreaks of this disease have been increasingly reported in fish farms in the western region of Ukraine. Moreover, this parasite is most commonly found in larger quantities in young fish. The aim of this study was to investigate the effect of the drug “Brovermectin-Granulat™” and ground milk thistle fruits on the levels of lipid peroxidation products and the activity of the enzymatic component of the antioxidant defense system in the hepatopancreas of one-year-old scale carp infected with Eudiplozoon nipponicum. The research was conducted in the pond fish farms of the State Enterprise “Rybgosp “Halytsky” (now LLC “Rybgosp “Burshtynskyi”) in the Rohatyn district of Ivano-Frankivsk region and in the private farm “Dobrotvirskyi fish factory” in the Kamyanka-Buzka district of Lviv region, located in the warm waters of cooling ponds of the Burshtyn and Dobrotvir thermal power plants. One-year-old scale carp (with a body weight of 45–47 g), infected with Eudiplozoon nipponicum, were selected for the study. To examine the effects of “Brovermectin-Granulat™” and milk thistle fruits on lipid peroxidation products and the antioxidant system enzymes in the hepatopancreas, we formed three groups of fish, with 6 specimens in each group: a control group – fish infected with monogeneans, an experimental group I – fish treated with the antiparasitic drug “Brovermectin-Granulat™” (at a dose of 60 mg/kg body weight), experimental group II – fish treated with “Brovermectin-Granulat™” (at a dose of 60 mg/kg body weight) and ground milk thistle fruits (5 % of the compound feed was supplemented with ground milk thistle fruits by granulation). The study of peroxide processes and the antioxidant system status in the hepatopancreas of one-year-old scale carp infected with Eudiplozoon nipponicum, and after the application of the above-mentioned drugs, showed that in the experimental groups of fish, a reduction in the levels of lipid peroxidation products was observed. It was also noted that the studied supplement based on ground milk thistle fruits had a stimulating effect on the antioxidant status of the fish, as evidenced by significantly higher activity of catalase, superoxide dismutase, and glutathione peroxidase in the hepatopancreas of the experimental fish.
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series Науковий вісник Львівського національного університету ветеринарної медицини та біотехнологій імені С.З. Гжицького. Серія: Сільськогосподарські науки
spelling doaj-art-c694e18441be4d619cf445cfcedaa0792025-08-20T02:21:34ZengStepan Gzhytskyi National University of Veterinary Medicine and Biotechnologies LvivНауковий вісник Львівського національного університету ветеринарної медицини та біотехнологій імені С.З. Гжицького. Серія: Сільськогосподарські науки2519-26982707-58342024-09-012610125826310.32718/nvlvet-a101405413Antioxidant status of one-year-old carp infected with Eudiplozoon nipponicum and the effects of corrective factorsO. V. Fedorovych0B. B. Saiuk1B. V. Gutyj2M. P. Drach3T. V. Martyshuk4S. I. Kravets5A. O. Boiko6U. M. Vus7O. Ye. Vozna8Kh. Ya. Leskiv9V. Ya. Momut10Stepan Gzhytskyi National University of Veterinary Medicine and Biotechnologies, Lviv, UkraineStepan Gzhytskyi National University of Veterinary Medicine and Biotechnologies, Lviv, UkraineStepan Gzhytskyi National University of Veterinary Medicine and Biotechnologies, Lviv, UkraineStepan Gzhytskyi National University of Veterinary Medicine and Biotechnologies, Lviv, UkraineStepan Gzhytskyi National University of Veterinary Medicine and Biotechnologies, Lviv, UkraineStepan Gzhytskyi National University of Veterinary Medicine and Biotechnologies, Lviv, UkraineStepan Gzhytskyi National University of Veterinary Medicine and Biotechnologies, Lviv, UkraineStepan Gzhytskyi National University of Veterinary Medicine and Biotechnologies, Lviv, UkraineStepan Gzhytskyi National University of Veterinary Medicine and Biotechnologies, Lviv, UkraineStepan Gzhytskyi National University of Veterinary Medicine and Biotechnologies, Lviv, UkraineStepan Gzhytskyi National University of Veterinary Medicine and Biotechnologies, Lviv, UkraineOne of the least studied monogeneosis diseases to date is carp diplostomosis. Outbreaks of this disease have been increasingly reported in fish farms in the western region of Ukraine. Moreover, this parasite is most commonly found in larger quantities in young fish. The aim of this study was to investigate the effect of the drug “Brovermectin-Granulat™” and ground milk thistle fruits on the levels of lipid peroxidation products and the activity of the enzymatic component of the antioxidant defense system in the hepatopancreas of one-year-old scale carp infected with Eudiplozoon nipponicum. The research was conducted in the pond fish farms of the State Enterprise “Rybgosp “Halytsky” (now LLC “Rybgosp “Burshtynskyi”) in the Rohatyn district of Ivano-Frankivsk region and in the private farm “Dobrotvirskyi fish factory” in the Kamyanka-Buzka district of Lviv region, located in the warm waters of cooling ponds of the Burshtyn and Dobrotvir thermal power plants. One-year-old scale carp (with a body weight of 45–47 g), infected with Eudiplozoon nipponicum, were selected for the study. To examine the effects of “Brovermectin-Granulat™” and milk thistle fruits on lipid peroxidation products and the antioxidant system enzymes in the hepatopancreas, we formed three groups of fish, with 6 specimens in each group: a control group – fish infected with monogeneans, an experimental group I – fish treated with the antiparasitic drug “Brovermectin-Granulat™” (at a dose of 60 mg/kg body weight), experimental group II – fish treated with “Brovermectin-Granulat™” (at a dose of 60 mg/kg body weight) and ground milk thistle fruits (5 % of the compound feed was supplemented with ground milk thistle fruits by granulation). The study of peroxide processes and the antioxidant system status in the hepatopancreas of one-year-old scale carp infected with Eudiplozoon nipponicum, and after the application of the above-mentioned drugs, showed that in the experimental groups of fish, a reduction in the levels of lipid peroxidation products was observed. It was also noted that the studied supplement based on ground milk thistle fruits had a stimulating effect on the antioxidant status of the fish, as evidenced by significantly higher activity of catalase, superoxide dismutase, and glutathione peroxidase in the hepatopancreas of the experimental fish.https://nvlvet.com.ua/index.php/agriculture/article/view/5413carp fish, eudiplozoon nipponicum, hepatopancreas, tbc products, dienic conjugates, hydroperoxides, superoxide dismutase, catalase, glutathione peroxidase, milk thistle.
spellingShingle O. V. Fedorovych
B. B. Saiuk
B. V. Gutyj
M. P. Drach
T. V. Martyshuk
S. I. Kravets
A. O. Boiko
U. M. Vus
O. Ye. Vozna
Kh. Ya. Leskiv
V. Ya. Momut
Antioxidant status of one-year-old carp infected with Eudiplozoon nipponicum and the effects of corrective factors
Науковий вісник Львівського національного університету ветеринарної медицини та біотехнологій імені С.З. Гжицького. Серія: Сільськогосподарські науки
carp fish, eudiplozoon nipponicum, hepatopancreas, tbc products, dienic conjugates, hydroperoxides, superoxide dismutase, catalase, glutathione peroxidase, milk thistle.
title Antioxidant status of one-year-old carp infected with Eudiplozoon nipponicum and the effects of corrective factors
title_full Antioxidant status of one-year-old carp infected with Eudiplozoon nipponicum and the effects of corrective factors
title_fullStr Antioxidant status of one-year-old carp infected with Eudiplozoon nipponicum and the effects of corrective factors
title_full_unstemmed Antioxidant status of one-year-old carp infected with Eudiplozoon nipponicum and the effects of corrective factors
title_short Antioxidant status of one-year-old carp infected with Eudiplozoon nipponicum and the effects of corrective factors
title_sort antioxidant status of one year old carp infected with eudiplozoon nipponicum and the effects of corrective factors
topic carp fish, eudiplozoon nipponicum, hepatopancreas, tbc products, dienic conjugates, hydroperoxides, superoxide dismutase, catalase, glutathione peroxidase, milk thistle.
url https://nvlvet.com.ua/index.php/agriculture/article/view/5413
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