Reserpine alleviates cisplatin-induced acute kidney injury via anti-ferroptosis and cGAS/STING pathway

Reserpine alleviates cisplatin-induced acute kidney injury via anti-ferroptosis and cGAS/STING pathway

Cisplatin plays a pivotal role in the chemotherapy treatment of various cancers, but its use is often limited due to its nephrotoxic side effects. Identifying compounds that can mitigate cisplatin-induced nephrotoxicity is therefore of great importance. This study focused on evaluating the protectiv...

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Bibliographic Details
Main Authors: Nahua Xu, Rong Mu, Siyuan Deng, Ye Han, Yanyun Shi, Xuemei Fu, Hui Li, Qi Yao
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Renal Failure
Subjects:
Reserpine
acute kidney injury
cisplatin
ferroptosis
Online Access:https://www.tandfonline.com/doi/10.1080/0886022X.2024.2406395
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