Evaluating the Impact of Argyreia Speciosa Gel versus Noneugenol Periodontal Dressing on Wound Healing and Pain Postperiodontal Flap Surgery: A Split-Mouth Randomized Clinical Trial
Aim: To compare the effect of topical application of Argyreia speciosa gel and noneugenol periodontal dressing on wound healing and pain following periodontal flap surgery. Introduction: Periodontal flap surgery is a leading treatment for managing periodontal pockets in chronic periodontitis. Healin...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2025-06-01
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| Series: | Journal of Pharmacy and Bioallied Sciences |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/jpbs.jpbs_895_24 |
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| Summary: | Aim:
To compare the effect of topical application of Argyreia speciosa gel and noneugenol periodontal dressing on wound healing and pain following periodontal flap surgery.
Introduction:
Periodontal flap surgery is a leading treatment for managing periodontal pockets in chronic periodontitis. Healing plays a crucial role in restoring periodontal tissue integrity. The necessity of postprocedure periodontal dressing is questioned due to evidence suggesting that thorough cleanliness alone can promote complete healing. Argyreia speciosa, a revered medicinal plant, known for its anti-inflammatory, antimicrobial, and analgesic properties.
Methodology:
Periodontal flap surgery was performed in 20 patients (40 sites). After flap surgery, patients were randomly assigned to Argyreia speciosa gel group or COE-PAK group. Early Healing Score (EHS) after 1st week and Healing Index (HI) and Visual Analog Scale (VAS) scoring was done after 1st and 2nd week.
Results:
The results indicated that the Argyreia speciosa gel group experienced significantly less pain, as measured by the VAS (P = 0.014), and demonstrated better wound healing, assessed through the EHS (P = 0.025) and HI (P = 0.014), compared to the periodontal dressing group during the first week. These differences were statistically significant. However, by the second week, the differences in HI and VAS scores between the Argyreia speciosa gel group and the periodontal dressing group were not statistically significant.
Conclusion:
Argyreia speciosa gel exhibits efficacy superior to noneugenol periodontal dressing in promoting wound healing and reducing pain perception at first week, suggesting its potential as an alternative to noneugenol periodontal dressing after periodontal flap surgery. |
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| ISSN: | 0976-4879 0975-7406 |