A rare case of culture-negative infective endocarditis following cataract surgery
A 70-year-old man developed intermittent fever with chills, severe anorexia, generalized weakness, and mild exertional difficulty in breathing following posterior chamber intraocular lens replacement surgery for a mature white cataract in the left eye. Laboratory tests revealed persistent negative b...
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2025-01-01
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| Series: | Journal of International Medical Research |
| Online Access: | https://doi.org/10.1177/03000605241311778 |
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| author | Gayashani K. Jayasinghe Logeswaran Dinusha Udara S. Perera Indrakumar Jegarajah |
| author_facet | Gayashani K. Jayasinghe Logeswaran Dinusha Udara S. Perera Indrakumar Jegarajah |
| author_sort | Gayashani K. Jayasinghe |
| collection | DOAJ |
| description | A 70-year-old man developed intermittent fever with chills, severe anorexia, generalized weakness, and mild exertional difficulty in breathing following posterior chamber intraocular lens replacement surgery for a mature white cataract in the left eye. Laboratory tests revealed persistent negative blood cultures, normocytic and normochromic anemia, neutrophilia, and elevated inflammatory markers despite multiple courses of antibiotics. All other investigations conducted to identify the cause of prolonged fever, including transthoracic echocardiography, were negative. However, transesophageal echocardiography detected an aortic valve vegetation. The patient had no history of valvular disease or any predisposing condition for infective endocarditis. The bacteremia was strongly suspected to have resulted from cataract surgery, although no obvious signs of eye infection were observed during the postoperative period. The patient was treated with empirical antibiotics, including vancomycin and ceftriaxone, which led to significant improvement. Because infective endocarditis remains a significant public health concern with increasing incidence rates, we present this unusual case of culture-negative infective endocarditis following cataract surgery, highlighting the diagnostic and therapeutic challenges encountered. |
| format | Article |
| id | doaj-art-c66ebb8ccbd244fcb8c12fd36eff231c |
| institution | Kabale University |
| issn | 1473-2300 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Journal of International Medical Research |
| spelling | doaj-art-c66ebb8ccbd244fcb8c12fd36eff231c2025-01-29T12:04:06ZengSAGE PublishingJournal of International Medical Research1473-23002025-01-015310.1177/03000605241311778A rare case of culture-negative infective endocarditis following cataract surgeryGayashani K. JayasingheLogeswaran DinushaUdara S. PereraIndrakumar JegarajahA 70-year-old man developed intermittent fever with chills, severe anorexia, generalized weakness, and mild exertional difficulty in breathing following posterior chamber intraocular lens replacement surgery for a mature white cataract in the left eye. Laboratory tests revealed persistent negative blood cultures, normocytic and normochromic anemia, neutrophilia, and elevated inflammatory markers despite multiple courses of antibiotics. All other investigations conducted to identify the cause of prolonged fever, including transthoracic echocardiography, were negative. However, transesophageal echocardiography detected an aortic valve vegetation. The patient had no history of valvular disease or any predisposing condition for infective endocarditis. The bacteremia was strongly suspected to have resulted from cataract surgery, although no obvious signs of eye infection were observed during the postoperative period. The patient was treated with empirical antibiotics, including vancomycin and ceftriaxone, which led to significant improvement. Because infective endocarditis remains a significant public health concern with increasing incidence rates, we present this unusual case of culture-negative infective endocarditis following cataract surgery, highlighting the diagnostic and therapeutic challenges encountered.https://doi.org/10.1177/03000605241311778 |
| spellingShingle | Gayashani K. Jayasinghe Logeswaran Dinusha Udara S. Perera Indrakumar Jegarajah A rare case of culture-negative infective endocarditis following cataract surgery Journal of International Medical Research |
| title | A rare case of culture-negative infective endocarditis following cataract surgery |
| title_full | A rare case of culture-negative infective endocarditis following cataract surgery |
| title_fullStr | A rare case of culture-negative infective endocarditis following cataract surgery |
| title_full_unstemmed | A rare case of culture-negative infective endocarditis following cataract surgery |
| title_short | A rare case of culture-negative infective endocarditis following cataract surgery |
| title_sort | rare case of culture negative infective endocarditis following cataract surgery |
| url | https://doi.org/10.1177/03000605241311778 |
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