Machine Learning Decision Support for Macronutrients in Neonatal Parenteral Nutrition

Parenteral nutrition plays a crucial role in the care of hospitalized patients in the neonatal intensive care unit. Determining the appropriate amount and composition of parenteral nutrition bag for each infant is a complex and individualized process. Using a dataset of 1210 neonatal intensive-care...

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Main Authors: Setareh Derakhshandara, Valentina Franzoni, Daniele Mezzetti, Valentina Poggioni
Format: Article
Language:English
Published: IEEE 2024-01-01
Series:IEEE Access
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Online Access:https://ieeexplore.ieee.org/document/10752961/
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author Setareh Derakhshandara
Valentina Franzoni
Daniele Mezzetti
Valentina Poggioni
author_facet Setareh Derakhshandara
Valentina Franzoni
Daniele Mezzetti
Valentina Poggioni
author_sort Setareh Derakhshandara
collection DOAJ
description Parenteral nutrition plays a crucial role in the care of hospitalized patients in the neonatal intensive care unit. Determining the appropriate amount and composition of parenteral nutrition bag for each infant is a complex and individualized process. Using a dataset of 1210 neonatal intensive-care unit patients of the University Hospital of Perugia, collected over 17 years, this work aims to establish the basis for an evidence-based decision support system to reduce the time and effort required for manual calculations from doctors working in such a critical emergency environment. After the data was presented, we compared different machine learning techniques (i.e., random forest, gradient boosting machine, support vector machine, multilayer perceptron) that could predict nutritional requirements. We discuss the feasibility of the proposed approach, evaluating the methods in terms of their explainability, and using performance measures (i.e., RMSE, <inline-formula> <tex-math notation="LaTeX">$R^{2}$ </tex-math></inline-formula>). Preliminary results revealed promising predictive ability for macronutrients and volume of parenteral bags. These findings highlight the potential of machine learning as a valuable tool for nutritional outcome estimation in neonatal clinical practice.
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spelling doaj-art-c65853f2eeed471ca075089fbf4260742025-08-20T02:22:40ZengIEEEIEEE Access2169-35362024-01-011217000117001010.1109/ACCESS.2024.349805910752961Machine Learning Decision Support for Macronutrients in Neonatal Parenteral NutritionSetareh Derakhshandara0Valentina Franzoni1https://orcid.org/0000-0002-2972-7188Daniele Mezzetti2https://orcid.org/0000-0001-7612-4382Valentina Poggioni3https://orcid.org/0000-0002-7691-7478Department of Mathematics and Computer Science, University of Perugia, Perugia, ItalyDepartment of Mathematics and Computer Science, University of Perugia, Perugia, ItalyNeonatal Intensive Care Unit, Santa Maria della Misericordia Hospital of Perugia, Perugia, ItalyDepartment of Mathematics and Computer Science, University of Perugia, Perugia, ItalyParenteral nutrition plays a crucial role in the care of hospitalized patients in the neonatal intensive care unit. Determining the appropriate amount and composition of parenteral nutrition bag for each infant is a complex and individualized process. Using a dataset of 1210 neonatal intensive-care unit patients of the University Hospital of Perugia, collected over 17 years, this work aims to establish the basis for an evidence-based decision support system to reduce the time and effort required for manual calculations from doctors working in such a critical emergency environment. After the data was presented, we compared different machine learning techniques (i.e., random forest, gradient boosting machine, support vector machine, multilayer perceptron) that could predict nutritional requirements. We discuss the feasibility of the proposed approach, evaluating the methods in terms of their explainability, and using performance measures (i.e., RMSE, <inline-formula> <tex-math notation="LaTeX">$R^{2}$ </tex-math></inline-formula>). Preliminary results revealed promising predictive ability for macronutrients and volume of parenteral bags. These findings highlight the potential of machine learning as a valuable tool for nutritional outcome estimation in neonatal clinical practice.https://ieeexplore.ieee.org/document/10752961/Machine learningintelligent decision systemsneonatal intensive careAI for decision in healthcaremachine learning for parenteral nutritioninfant nutrition
spellingShingle Setareh Derakhshandara
Valentina Franzoni
Daniele Mezzetti
Valentina Poggioni
Machine Learning Decision Support for Macronutrients in Neonatal Parenteral Nutrition
IEEE Access
Machine learning
intelligent decision systems
neonatal intensive care
AI for decision in healthcare
machine learning for parenteral nutrition
infant nutrition
title Machine Learning Decision Support for Macronutrients in Neonatal Parenteral Nutrition
title_full Machine Learning Decision Support for Macronutrients in Neonatal Parenteral Nutrition
title_fullStr Machine Learning Decision Support for Macronutrients in Neonatal Parenteral Nutrition
title_full_unstemmed Machine Learning Decision Support for Macronutrients in Neonatal Parenteral Nutrition
title_short Machine Learning Decision Support for Macronutrients in Neonatal Parenteral Nutrition
title_sort machine learning decision support for macronutrients in neonatal parenteral nutrition
topic Machine learning
intelligent decision systems
neonatal intensive care
AI for decision in healthcare
machine learning for parenteral nutrition
infant nutrition
url https://ieeexplore.ieee.org/document/10752961/
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AT valentinafranzoni machinelearningdecisionsupportformacronutrientsinneonatalparenteralnutrition
AT danielemezzetti machinelearningdecisionsupportformacronutrientsinneonatalparenteralnutrition
AT valentinapoggioni machinelearningdecisionsupportformacronutrientsinneonatalparenteralnutrition