Role of inflammasomes in cancer immunity: mechanisms and therapeutic potential

Abstract Inflammasomes are multi-protein complexes that detect pathogenic and damage-associated molecular patterns, activating caspase-1, pyroptosis, and the maturation of pro-inflammatory cytokines such as IL-1β and IL-18Within the tumor microenvironment, inflammasomes like NLRP3 play critical role...

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Bibliographic Details
Main Authors: Vivek Singh, Saba Ubaid, Mohammad Kashif, Tanvi Singh, Gaurav Singh, Roma Pahwa, Anand Singh
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Online Access:https://doi.org/10.1186/s13046-025-03366-y
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