The Prechtl’s General Movement Assessment, Hammersmith Infant Neurological Examination and Sensory Profile-2 in Prediction of Cerebral Palsy at Two Years of Age in High-risk Infants: A Retrospective Study
Objective: The predictive values of the general movements assessment (GMA), the Hammersmith infant neurological examination (HINE), and the infant sensory profile-2 (ISP-2) were investigated for the diagnosis of cerebral palsy (CP) in high-risk infants at two years age. Methods: Thirty-four high-ri...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Galenos Publishing House
2025-01-01
|
| Series: | Bezmiâlem Science |
| Subjects: | |
| Online Access: | https://www.bezmialemscience.org/articles/the-prechtls-general-movement-assessment-hammersmith-infant-neurological-examination-and-sensory-profile-2-in-prediction-of-cerebral-palsy-at-two-years-of-age-in-high-risk-infants-a-retrospective-study/doi/bas.galenos.2024.48344 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832584750747877376 |
|---|---|
| author | Hatice ADIGÜZEL Halil İbrahim ÇELİK Yusuf Ünal SARIKABADAYI Nevin ERGUN Bülent ELBASAN |
| author_facet | Hatice ADIGÜZEL Halil İbrahim ÇELİK Yusuf Ünal SARIKABADAYI Nevin ERGUN Bülent ELBASAN |
| author_sort | Hatice ADIGÜZEL |
| collection | DOAJ |
| description | Objective: The predictive values of the general movements assessment (GMA), the Hammersmith infant neurological examination (HINE), and the infant sensory profile-2 (ISP-2) were investigated for the diagnosis of cerebral palsy (CP) in high-risk infants at two years age.
Methods: Thirty-four high-risk infants with a mean gestational age of 33.1±4.2, who were followed up in the physiotherapy unit after discharge from the neonatal intensive care unit, were recruited. Prechtl’s GMA results were collected for infants at 3rd month. The ISP-2 and HINE were used to evaluate neurological and sensory processing at 3rd month for once, respectively. A pediatric neurologist who was blinded to all testing made the diagnosis of CP at two years of age based on neuroimaging and clinical tests. The GMA, HINE, and ISP-2’s predictive values were assessed seperately and sequentially (with two and three stage testings).
Results: The mean birth weight of the infants was 1993.7±889.3 grams (g), the 3rd month HINE and ISP-2 total score averages were 56.9±9.3 and 53.8±13, respectively. In order to diagnose CP, it was important to consider the predictive values of the GMA (absent FMs) (sensitivity: 100%; specificity: 96.15%, p<0.001; 95% confidence interval: 80.36-99.9), HINE (sensitivity: 87.5%; specificity: 80.77%; p=0.004), and the combination of both GMA and HINE (sensitivity: 87.5%; specificity: 100%; p<0.001). The combination of ISP-2, GMA, and HINE was significant in identifying CP diagnosis (sensitivity: 62.5%, specificity: 100%, p=0.002) despite the ISP-2’s unremarkable predictive performance (sensitivity: 75%, specificity: 61.54%, p=0.123).
Conlusion: Early follow-up of high-risk of infants may enable early diagnosis of CP and referral to early intervention by clinical application and combination of GMA and HINE. |
| format | Article |
| id | doaj-art-c65265ed685242c8989fa237ad77bd75 |
| institution | Kabale University |
| issn | 2148-2373 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Galenos Publishing House |
| record_format | Article |
| series | Bezmiâlem Science |
| spelling | doaj-art-c65265ed685242c8989fa237ad77bd752025-01-27T12:14:30ZengGalenos Publishing HouseBezmiâlem Science2148-23732025-01-011311910.14235/bas.galenos.2024.48344The Prechtl’s General Movement Assessment, Hammersmith Infant Neurological Examination and Sensory Profile-2 in Prediction of Cerebral Palsy at Two Years of Age in High-risk Infants: A Retrospective StudyHatice ADIGÜZEL0https://orcid.org/0000-0001-9323-839XHalil İbrahim ÇELİK1https://orcid.org/0000-0003-3849-6382Yusuf Ünal SARIKABADAYI2https://orcid.org/0000-0003-3953-9137Nevin ERGUN3https://orcid.org/0000-0001-6575-7205Bülent ELBASAN4https://orcid.org/0000-0001-8714-0214Kahramanmaraş Sütçü İmam University Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation, Kahramanmaraş, TürkiyeBilge Çocuk Special Education and Rehabilitation Center, Ankara, TürkiyeSanko University Faculty of Medicine, Department of Pediatrics, Gaziantep, TürkiyeSanko University Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation, Gaziantep, TürkiyeGazi University Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation, Ankara, TürkiyeObjective: The predictive values of the general movements assessment (GMA), the Hammersmith infant neurological examination (HINE), and the infant sensory profile-2 (ISP-2) were investigated for the diagnosis of cerebral palsy (CP) in high-risk infants at two years age. Methods: Thirty-four high-risk infants with a mean gestational age of 33.1±4.2, who were followed up in the physiotherapy unit after discharge from the neonatal intensive care unit, were recruited. Prechtl’s GMA results were collected for infants at 3rd month. The ISP-2 and HINE were used to evaluate neurological and sensory processing at 3rd month for once, respectively. A pediatric neurologist who was blinded to all testing made the diagnosis of CP at two years of age based on neuroimaging and clinical tests. The GMA, HINE, and ISP-2’s predictive values were assessed seperately and sequentially (with two and three stage testings). Results: The mean birth weight of the infants was 1993.7±889.3 grams (g), the 3rd month HINE and ISP-2 total score averages were 56.9±9.3 and 53.8±13, respectively. In order to diagnose CP, it was important to consider the predictive values of the GMA (absent FMs) (sensitivity: 100%; specificity: 96.15%, p<0.001; 95% confidence interval: 80.36-99.9), HINE (sensitivity: 87.5%; specificity: 80.77%; p=0.004), and the combination of both GMA and HINE (sensitivity: 87.5%; specificity: 100%; p<0.001). The combination of ISP-2, GMA, and HINE was significant in identifying CP diagnosis (sensitivity: 62.5%, specificity: 100%, p=0.002) despite the ISP-2’s unremarkable predictive performance (sensitivity: 75%, specificity: 61.54%, p=0.123). Conlusion: Early follow-up of high-risk of infants may enable early diagnosis of CP and referral to early intervention by clinical application and combination of GMA and HINE.https://www.bezmialemscience.org/articles/the-prechtls-general-movement-assessment-hammersmith-infant-neurological-examination-and-sensory-profile-2-in-prediction-of-cerebral-palsy-at-two-years-of-age-in-high-risk-infants-a-retrospective-study/doi/bas.galenos.2024.48344general movement assessmenthammersmith infant neurological examinationinfant sensory profile-2cerebral palsyhigh risk infant |
| spellingShingle | Hatice ADIGÜZEL Halil İbrahim ÇELİK Yusuf Ünal SARIKABADAYI Nevin ERGUN Bülent ELBASAN The Prechtl’s General Movement Assessment, Hammersmith Infant Neurological Examination and Sensory Profile-2 in Prediction of Cerebral Palsy at Two Years of Age in High-risk Infants: A Retrospective Study Bezmiâlem Science general movement assessment hammersmith infant neurological examination infant sensory profile-2 cerebral palsy high risk infant |
| title | The Prechtl’s General Movement Assessment, Hammersmith Infant Neurological Examination and Sensory Profile-2 in Prediction of Cerebral Palsy at Two Years of Age in High-risk Infants: A Retrospective Study |
| title_full | The Prechtl’s General Movement Assessment, Hammersmith Infant Neurological Examination and Sensory Profile-2 in Prediction of Cerebral Palsy at Two Years of Age in High-risk Infants: A Retrospective Study |
| title_fullStr | The Prechtl’s General Movement Assessment, Hammersmith Infant Neurological Examination and Sensory Profile-2 in Prediction of Cerebral Palsy at Two Years of Age in High-risk Infants: A Retrospective Study |
| title_full_unstemmed | The Prechtl’s General Movement Assessment, Hammersmith Infant Neurological Examination and Sensory Profile-2 in Prediction of Cerebral Palsy at Two Years of Age in High-risk Infants: A Retrospective Study |
| title_short | The Prechtl’s General Movement Assessment, Hammersmith Infant Neurological Examination and Sensory Profile-2 in Prediction of Cerebral Palsy at Two Years of Age in High-risk Infants: A Retrospective Study |
| title_sort | prechtl s general movement assessment hammersmith infant neurological examination and sensory profile 2 in prediction of cerebral palsy at two years of age in high risk infants a retrospective study |
| topic | general movement assessment hammersmith infant neurological examination infant sensory profile-2 cerebral palsy high risk infant |
| url | https://www.bezmialemscience.org/articles/the-prechtls-general-movement-assessment-hammersmith-infant-neurological-examination-and-sensory-profile-2-in-prediction-of-cerebral-palsy-at-two-years-of-age-in-high-risk-infants-a-retrospective-study/doi/bas.galenos.2024.48344 |
| work_keys_str_mv | AT haticeadiguzel theprechtlsgeneralmovementassessmenthammersmithinfantneurologicalexaminationandsensoryprofile2inpredictionofcerebralpalsyattwoyearsofageinhighriskinfantsaretrospectivestudy AT halilibrahimcelik theprechtlsgeneralmovementassessmenthammersmithinfantneurologicalexaminationandsensoryprofile2inpredictionofcerebralpalsyattwoyearsofageinhighriskinfantsaretrospectivestudy AT yusufunalsarikabadayi theprechtlsgeneralmovementassessmenthammersmithinfantneurologicalexaminationandsensoryprofile2inpredictionofcerebralpalsyattwoyearsofageinhighriskinfantsaretrospectivestudy AT nevinergun theprechtlsgeneralmovementassessmenthammersmithinfantneurologicalexaminationandsensoryprofile2inpredictionofcerebralpalsyattwoyearsofageinhighriskinfantsaretrospectivestudy AT bulentelbasan theprechtlsgeneralmovementassessmenthammersmithinfantneurologicalexaminationandsensoryprofile2inpredictionofcerebralpalsyattwoyearsofageinhighriskinfantsaretrospectivestudy AT haticeadiguzel prechtlsgeneralmovementassessmenthammersmithinfantneurologicalexaminationandsensoryprofile2inpredictionofcerebralpalsyattwoyearsofageinhighriskinfantsaretrospectivestudy AT halilibrahimcelik prechtlsgeneralmovementassessmenthammersmithinfantneurologicalexaminationandsensoryprofile2inpredictionofcerebralpalsyattwoyearsofageinhighriskinfantsaretrospectivestudy AT yusufunalsarikabadayi prechtlsgeneralmovementassessmenthammersmithinfantneurologicalexaminationandsensoryprofile2inpredictionofcerebralpalsyattwoyearsofageinhighriskinfantsaretrospectivestudy AT nevinergun prechtlsgeneralmovementassessmenthammersmithinfantneurologicalexaminationandsensoryprofile2inpredictionofcerebralpalsyattwoyearsofageinhighriskinfantsaretrospectivestudy AT bulentelbasan prechtlsgeneralmovementassessmenthammersmithinfantneurologicalexaminationandsensoryprofile2inpredictionofcerebralpalsyattwoyearsofageinhighriskinfantsaretrospectivestudy |