Xanthogranulomatous Pyelonephritis Incidentally Detected in a Young Infant
Background: Xanthogranulomatous pyelonephritis (XGP) is a chronic inflammatory condition of the kidney, rarely reported in children, and often misdiagnosed as a neoplasm. Clinical Description: A 2-month-old preterm baby boy was hospitalized for bronchiolitis. Examination showed tachypnea, normal pul...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2024-11-01
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| Series: | Indian Pediatrics Case Reports |
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| Online Access: | https://journals.lww.com/10.4103/ipcares.ipcares_169_24 |
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| author | Jeena Annie Philip R. Veena Christy Cathreen Thomas Radhika C. Radhakrishnan Ashok Kumar Susan Uthup |
| author_facet | Jeena Annie Philip R. Veena Christy Cathreen Thomas Radhika C. Radhakrishnan Ashok Kumar Susan Uthup |
| author_sort | Jeena Annie Philip |
| collection | DOAJ |
| description | Background:
Xanthogranulomatous pyelonephritis (XGP) is a chronic inflammatory condition of the kidney, rarely reported in children, and often misdiagnosed as a neoplasm.
Clinical Description:
A 2-month-old preterm baby boy was hospitalized for bronchiolitis. Examination showed tachypnea, normal pulses, improper weight gain since birth, hypertension and was incidentally detected to have palpable right kidney, without any abnormality in urinary stream.
Management and Outcome:
Routine blood investigations and urinalysis were normal. Chest X-ray was consistent with bronchiolitis and the baby was managed accordingly along with nifedipine for hypertension. Ultrasound abdomen showed an enlarged right kidney with hypoechoic mass in the upper pole and magnetic resonance imaging further showed the mass having areas of necrosis infiltrating into surrounding tissues. Considering a possibility of neoplasm, nephrectomy was performed. However, histopathological evaluation showed evidence of XGP. The baby thrived well, postnephrectomy and remained asymptomatic.
Conclusion:
This case creates awareness regarding occurrence of XGP in such a young infant, where diagnosis was made incidentally, only during a thorough systemic examination, followed by radiological imaging and histopathology. |
| format | Article |
| id | doaj-art-c64f343d3287491aa8fd18b38e8ba06e |
| institution | Kabale University |
| issn | 2772-5170 2772-5189 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Pediatrics Case Reports |
| spelling | doaj-art-c64f343d3287491aa8fd18b38e8ba06e2024-12-10T08:53:35ZengWolters Kluwer Medknow PublicationsIndian Pediatrics Case Reports2772-51702772-51892024-11-014424124310.4103/ipcares.ipcares_169_24Xanthogranulomatous Pyelonephritis Incidentally Detected in a Young InfantJeena Annie PhilipR. VeenaChristy Cathreen ThomasRadhika C. RadhakrishnanAshok KumarSusan UthupBackground: Xanthogranulomatous pyelonephritis (XGP) is a chronic inflammatory condition of the kidney, rarely reported in children, and often misdiagnosed as a neoplasm. Clinical Description: A 2-month-old preterm baby boy was hospitalized for bronchiolitis. Examination showed tachypnea, normal pulses, improper weight gain since birth, hypertension and was incidentally detected to have palpable right kidney, without any abnormality in urinary stream. Management and Outcome: Routine blood investigations and urinalysis were normal. Chest X-ray was consistent with bronchiolitis and the baby was managed accordingly along with nifedipine for hypertension. Ultrasound abdomen showed an enlarged right kidney with hypoechoic mass in the upper pole and magnetic resonance imaging further showed the mass having areas of necrosis infiltrating into surrounding tissues. Considering a possibility of neoplasm, nephrectomy was performed. However, histopathological evaluation showed evidence of XGP. The baby thrived well, postnephrectomy and remained asymptomatic. Conclusion: This case creates awareness regarding occurrence of XGP in such a young infant, where diagnosis was made incidentally, only during a thorough systemic examination, followed by radiological imaging and histopathology.https://journals.lww.com/10.4103/ipcares.ipcares_169_24infantneoplasmnephrectomypyelonephritiswilm’s tumor |
| spellingShingle | Jeena Annie Philip R. Veena Christy Cathreen Thomas Radhika C. Radhakrishnan Ashok Kumar Susan Uthup Xanthogranulomatous Pyelonephritis Incidentally Detected in a Young Infant Indian Pediatrics Case Reports infant neoplasm nephrectomy pyelonephritis wilm’s tumor |
| title | Xanthogranulomatous Pyelonephritis Incidentally Detected in a Young Infant |
| title_full | Xanthogranulomatous Pyelonephritis Incidentally Detected in a Young Infant |
| title_fullStr | Xanthogranulomatous Pyelonephritis Incidentally Detected in a Young Infant |
| title_full_unstemmed | Xanthogranulomatous Pyelonephritis Incidentally Detected in a Young Infant |
| title_short | Xanthogranulomatous Pyelonephritis Incidentally Detected in a Young Infant |
| title_sort | xanthogranulomatous pyelonephritis incidentally detected in a young infant |
| topic | infant neoplasm nephrectomy pyelonephritis wilm’s tumor |
| url | https://journals.lww.com/10.4103/ipcares.ipcares_169_24 |
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