Impairments of Syntactic Comprehension in Korean and the Location of Ischemic Stroke Lesions: A Voxel-Based Lesion-Symptom Mapping Study

In order to assess the capacity of neurological patients to process syntactic features unique to Korean, such as the heavy dependence of parsing on syntactic morphemes rather than the word order in a sentence, the Korean Syntactic Comprehension Test (KSCT) was newly developed. To examine the correla...

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Main Authors: M. J. Kim, H. A. Jeon, K. M. Lee
Format: Article
Language:English
Published: Wiley 2010-01-01
Series:Behavioural Neurology
Online Access:http://dx.doi.org/10.3233/BEN-2009-0254
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author M. J. Kim
H. A. Jeon
K. M. Lee
author_facet M. J. Kim
H. A. Jeon
K. M. Lee
author_sort M. J. Kim
collection DOAJ
description In order to assess the capacity of neurological patients to process syntactic features unique to Korean, such as the heavy dependence of parsing on syntactic morphemes rather than the word order in a sentence, the Korean Syntactic Comprehension Test (KSCT) was newly developed. To examine the correlation between lesion locations and the test performance, we did voxel-based lesion-symptom mapping (VLSM) analysis in a group of 39 patients with ischemic stroke. As a result, KSCT scores of the aphasic patients were significantly lower than those of 18 normal subjects. Within the patient group, VLSM analysis showed significant association between lower KSCT performance and the lesions mainly located in left perisylvian area and anterior temporal lobe. The KSCT results were also closely correlated with the results of two subtests in the Korean version-the Western Aphasia Battery. We conclude therefore that brain localization of syntactic comprehension in Korean native speakers is similar to that in other language speakers, despite the unique features of the Korean syntax, and that the KSCT will be of diagnostic value in assessing left fronto-temporal functions in Korean patients.
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spelling doaj-art-c64ab382b2fb4a368a7b7773c9cbf1422025-08-20T03:23:22ZengWileyBehavioural Neurology0953-41801875-85842010-01-01221-231010.3233/BEN-2009-0254Impairments of Syntactic Comprehension in Korean and the Location of Ischemic Stroke Lesions: A Voxel-Based Lesion-Symptom Mapping StudyM. J. Kim0H. A. Jeon1K. M. Lee2Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of KoreaNeuroscience Research Institute, Gachon Medical School, Incheon, Republic of KoreaDepartment of Neurology, Seoul National University Hospital, Seoul, Republic of KoreaIn order to assess the capacity of neurological patients to process syntactic features unique to Korean, such as the heavy dependence of parsing on syntactic morphemes rather than the word order in a sentence, the Korean Syntactic Comprehension Test (KSCT) was newly developed. To examine the correlation between lesion locations and the test performance, we did voxel-based lesion-symptom mapping (VLSM) analysis in a group of 39 patients with ischemic stroke. As a result, KSCT scores of the aphasic patients were significantly lower than those of 18 normal subjects. Within the patient group, VLSM analysis showed significant association between lower KSCT performance and the lesions mainly located in left perisylvian area and anterior temporal lobe. The KSCT results were also closely correlated with the results of two subtests in the Korean version-the Western Aphasia Battery. We conclude therefore that brain localization of syntactic comprehension in Korean native speakers is similar to that in other language speakers, despite the unique features of the Korean syntax, and that the KSCT will be of diagnostic value in assessing left fronto-temporal functions in Korean patients.http://dx.doi.org/10.3233/BEN-2009-0254
spellingShingle M. J. Kim
H. A. Jeon
K. M. Lee
Impairments of Syntactic Comprehension in Korean and the Location of Ischemic Stroke Lesions: A Voxel-Based Lesion-Symptom Mapping Study
Behavioural Neurology
title Impairments of Syntactic Comprehension in Korean and the Location of Ischemic Stroke Lesions: A Voxel-Based Lesion-Symptom Mapping Study
title_full Impairments of Syntactic Comprehension in Korean and the Location of Ischemic Stroke Lesions: A Voxel-Based Lesion-Symptom Mapping Study
title_fullStr Impairments of Syntactic Comprehension in Korean and the Location of Ischemic Stroke Lesions: A Voxel-Based Lesion-Symptom Mapping Study
title_full_unstemmed Impairments of Syntactic Comprehension in Korean and the Location of Ischemic Stroke Lesions: A Voxel-Based Lesion-Symptom Mapping Study
title_short Impairments of Syntactic Comprehension in Korean and the Location of Ischemic Stroke Lesions: A Voxel-Based Lesion-Symptom Mapping Study
title_sort impairments of syntactic comprehension in korean and the location of ischemic stroke lesions a voxel based lesion symptom mapping study
url http://dx.doi.org/10.3233/BEN-2009-0254
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