Heart damage during meningococcal infection
Background. Meningococcal infection (MI) remains relevant in the modern world. In the Russian Federation, there is currently an increase in cases of meningococcal infection in the adult population. While the generalized form of meningococcal infection presents a recognizable clinical picture with th...
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| Format: | Article |
| Language: | Russian |
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Open Systems Publication
2024-12-01
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| Series: | Лечащий Врач |
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| Online Access: | https://journal.lvrach.ru/jour/article/view/1326 |
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| author | A. A. Grishaeva L. K. Alimova A. M. Domkina Zh. B. Ponezheva V. V. Maleev |
| author_facet | A. A. Grishaeva L. K. Alimova A. M. Domkina Zh. B. Ponezheva V. V. Maleev |
| author_sort | A. A. Grishaeva |
| collection | DOAJ |
| description | Background. Meningococcal infection (MI) remains relevant in the modern world. In the Russian Federation, there is currently an increase in cases of meningococcal infection in the adult population. While the generalized form of meningococcal infection presents a recognizable clinical picture with the development of hemorrhagic rash and meningitis, localized and rare forms of this infection are diagnosed extremely rarely. The true proportion of rare forms in the structure of meningococcal infection remains unknown. Cardiac involvement is the most commonly registered rare form of meningococcal infection after pneumonia; it can manifest as endocarditis, myocarditis, and pericarditis. The present paper provides a literature review of available data on the forms, pathogenesis, clinical picture, diagnosis, and approaches to the treatment of meningococcal pericarditis, myocarditis, and endocarditis. The nonspecificity of clinical symptoms and laboratory tests makes it difficult to suspect meningococcal infection in patients with cardiac infections. The lack of availability in real clinical practice of diagnostic methods such as MRI, endomyocardial biopsy, and pericardiocentesis leads to low detection of these forms, especially in patients with isolated cardiac involvement of meningococcal etiology. The need for selective nutrient media to detect the pathogen also contributes to the lack of identification of the etiological factor.Conclusion. A significant problem is the absence of clinical recommendations and treatment protocols for meningococcal cardiac involvement in patients without signs of the generalized form of MI. The complexity of diagnosing and treating meningococcal pericarditis is illustrated in the present paper by a clinical example. |
| format | Article |
| id | doaj-art-c649528ab63a448b9b79567779c8e3fb |
| institution | Kabale University |
| issn | 1560-5175 2687-1181 |
| language | Russian |
| publishDate | 2024-12-01 |
| publisher | Open Systems Publication |
| record_format | Article |
| series | Лечащий Врач |
| spelling | doaj-art-c649528ab63a448b9b79567779c8e3fb2025-08-20T03:57:51ZrusOpen Systems PublicationЛечащий Врач1560-51752687-11812024-12-01012323810.51793/OS.2024.27.12.0051313Heart damage during meningococcal infectionA. A. Grishaeva0L. K. Alimova1A. M. Domkina2Zh. B. Ponezheva3V. V. Maleev4Moscow Multidisciplinary Clinical Center "Kommunarka" of the Department of Health of the city of Moscow; Central Research Institute of EpidemiologyMoscow Multidisciplinary Clinical Center "Kommunarka" of the Department of Health of the city of Moscow; Central Research Institute of EpidemiologyMoscow Multidisciplinary Clinical Center "Kommunarka" of the Department of Health of the city of Moscow; Central Research Institute of EpidemiologyCentral Research Institute of EpidemiologyCentral Research Institute of EpidemiologyBackground. Meningococcal infection (MI) remains relevant in the modern world. In the Russian Federation, there is currently an increase in cases of meningococcal infection in the adult population. While the generalized form of meningococcal infection presents a recognizable clinical picture with the development of hemorrhagic rash and meningitis, localized and rare forms of this infection are diagnosed extremely rarely. The true proportion of rare forms in the structure of meningococcal infection remains unknown. Cardiac involvement is the most commonly registered rare form of meningococcal infection after pneumonia; it can manifest as endocarditis, myocarditis, and pericarditis. The present paper provides a literature review of available data on the forms, pathogenesis, clinical picture, diagnosis, and approaches to the treatment of meningococcal pericarditis, myocarditis, and endocarditis. The nonspecificity of clinical symptoms and laboratory tests makes it difficult to suspect meningococcal infection in patients with cardiac infections. The lack of availability in real clinical practice of diagnostic methods such as MRI, endomyocardial biopsy, and pericardiocentesis leads to low detection of these forms, especially in patients with isolated cardiac involvement of meningococcal etiology. The need for selective nutrient media to detect the pathogen also contributes to the lack of identification of the etiological factor.Conclusion. A significant problem is the absence of clinical recommendations and treatment protocols for meningococcal cardiac involvement in patients without signs of the generalized form of MI. The complexity of diagnosing and treating meningococcal pericarditis is illustrated in the present paper by a clinical example.https://journal.lvrach.ru/jour/article/view/1326meningococcal infectionmeningococcal pericarditismeningococcal myocarditismeningococcal endocarditis |
| spellingShingle | A. A. Grishaeva L. K. Alimova A. M. Domkina Zh. B. Ponezheva V. V. Maleev Heart damage during meningococcal infection Лечащий Врач meningococcal infection meningococcal pericarditis meningococcal myocarditis meningococcal endocarditis |
| title | Heart damage during meningococcal infection |
| title_full | Heart damage during meningococcal infection |
| title_fullStr | Heart damage during meningococcal infection |
| title_full_unstemmed | Heart damage during meningococcal infection |
| title_short | Heart damage during meningococcal infection |
| title_sort | heart damage during meningococcal infection |
| topic | meningococcal infection meningococcal pericarditis meningococcal myocarditis meningococcal endocarditis |
| url | https://journal.lvrach.ru/jour/article/view/1326 |
| work_keys_str_mv | AT aagrishaeva heartdamageduringmeningococcalinfection AT lkalimova heartdamageduringmeningococcalinfection AT amdomkina heartdamageduringmeningococcalinfection AT zhbponezheva heartdamageduringmeningococcalinfection AT vvmaleev heartdamageduringmeningococcalinfection |