RANKL Cytokine: From Pioneer of the Osteoimmunology Era to Cure for a Rare Disease
Since its identification, the RANKL cytokine has been demonstrated to play a crucial role in bone homeostasis and lymphoid tissue organization. Genetic defects impairing its function lead to a peculiar form of autosomal recessive osteopetrosis (ARO), a rare genetic bone disease presenting early in l...
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| Main Authors: | Nadia Lo Iacono, Alessandra Pangrazio, Mario Abinun, Robbert Bredius, Marco Zecca, Harry C. Blair, Paolo Vezzoni, Anna Villa, Cristina Sobacchi |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2013-01-01
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| Series: | Clinical and Developmental Immunology |
| Online Access: | http://dx.doi.org/10.1155/2013/412768 |
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