Acute oral toxicity and mucosal irritation of a mouthwash containing chlorhexidine and chlorine dioxide in animal models

Background: Halitosis is primarily caused by bacterial activity in the oral cavity. Chlorhexidine (CHX) is a widely used antimicrobial mouthwash but has notable side effects. Chlorine dioxide (ClO2) is a potent oxidizer that may reduce the required CHX concentration while preserving efficacy. This s...

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Bibliographic Details
Main Authors: Thao Thi Phuong Tran, Lam Nguyen Le, Thanh Van Tran, Thuy Anh Vu Pham
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Journal of Oral Biology and Craniofacial Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2212426825001046
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