Citrus Fruit-Based Calcium Titanate Anodization Coatings on Titanium Implants
With humans living longer and the median age of the population increasing, there is an ever-increasing demand for better biomedical implants. Titanium implants have a long history of successful use, but their naturally forming amorphous oxide surfaces are not ideal to promote bone growth. Therefore,...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2025-05-01
|
| Series: | Oxygen |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2673-9801/5/2/7 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849704948313358336 |
|---|---|
| author | Amisha Parekh Parker Knotts Amol V. Janorkar Michael D. Roach |
| author_facet | Amisha Parekh Parker Knotts Amol V. Janorkar Michael D. Roach |
| author_sort | Amisha Parekh |
| collection | DOAJ |
| description | With humans living longer and the median age of the population increasing, there is an ever-increasing demand for better biomedical implants. Titanium implants have a long history of successful use, but their naturally forming amorphous oxide surfaces are not ideal to promote bone growth. Therefore, titanium surfaces are often modified to improve bioactivity through electrochemical processes such as anodization which can crystallize the oxide into more bioactive titanium oxide phases, form hierarchical micro- and nano-scale roughness profiles, and incorporate beneficial bone chemistry into the oxide layer to improve interactions with bone cells. We have recently developed three innovative anodization electrolytes based on combinations of citrus fruit juices and commercially available calcium compounds. Anodization in these electrolytes produced citrus-based oxides exhibiting surface Ca/P ratios within the range of human bone, unique cauliflower-like hierarchical micro- and nano-scale surface roughness profiles, and the formation of titanate compounds which have been shown to be precursors for subsequent apatite formation. Thus, our titanate-containing citrus-based oxides show much promise for improving future osseointegration. |
| format | Article |
| id | doaj-art-c63efef5789f4bd6b80313ce2bfa2310 |
| institution | DOAJ |
| issn | 2673-9801 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Oxygen |
| spelling | doaj-art-c63efef5789f4bd6b80313ce2bfa23102025-08-20T03:16:35ZengMDPI AGOxygen2673-98012025-05-0152710.3390/oxygen5020007Citrus Fruit-Based Calcium Titanate Anodization Coatings on Titanium ImplantsAmisha Parekh0Parker Knotts1Amol V. Janorkar2Michael D. Roach3Department of Biomedical Materials Science, University of Mississippi Medical Center, Jackson, MS 39216, USADepartment of Biomedical Materials Science, University of Mississippi Medical Center, Jackson, MS 39216, USADepartment of Biomedical Materials Science, University of Mississippi Medical Center, Jackson, MS 39216, USADepartment of Biomedical Materials Science, University of Mississippi Medical Center, Jackson, MS 39216, USAWith humans living longer and the median age of the population increasing, there is an ever-increasing demand for better biomedical implants. Titanium implants have a long history of successful use, but their naturally forming amorphous oxide surfaces are not ideal to promote bone growth. Therefore, titanium surfaces are often modified to improve bioactivity through electrochemical processes such as anodization which can crystallize the oxide into more bioactive titanium oxide phases, form hierarchical micro- and nano-scale roughness profiles, and incorporate beneficial bone chemistry into the oxide layer to improve interactions with bone cells. We have recently developed three innovative anodization electrolytes based on combinations of citrus fruit juices and commercially available calcium compounds. Anodization in these electrolytes produced citrus-based oxides exhibiting surface Ca/P ratios within the range of human bone, unique cauliflower-like hierarchical micro- and nano-scale surface roughness profiles, and the formation of titanate compounds which have been shown to be precursors for subsequent apatite formation. Thus, our titanate-containing citrus-based oxides show much promise for improving future osseointegration.https://www.mdpi.com/2673-9801/5/2/7citrus-based oxidecalcium titanateanodizationosseointegrationtitanium implant |
| spellingShingle | Amisha Parekh Parker Knotts Amol V. Janorkar Michael D. Roach Citrus Fruit-Based Calcium Titanate Anodization Coatings on Titanium Implants Oxygen citrus-based oxide calcium titanate anodization osseointegration titanium implant |
| title | Citrus Fruit-Based Calcium Titanate Anodization Coatings on Titanium Implants |
| title_full | Citrus Fruit-Based Calcium Titanate Anodization Coatings on Titanium Implants |
| title_fullStr | Citrus Fruit-Based Calcium Titanate Anodization Coatings on Titanium Implants |
| title_full_unstemmed | Citrus Fruit-Based Calcium Titanate Anodization Coatings on Titanium Implants |
| title_short | Citrus Fruit-Based Calcium Titanate Anodization Coatings on Titanium Implants |
| title_sort | citrus fruit based calcium titanate anodization coatings on titanium implants |
| topic | citrus-based oxide calcium titanate anodization osseointegration titanium implant |
| url | https://www.mdpi.com/2673-9801/5/2/7 |
| work_keys_str_mv | AT amishaparekh citrusfruitbasedcalciumtitanateanodizationcoatingsontitaniumimplants AT parkerknotts citrusfruitbasedcalciumtitanateanodizationcoatingsontitaniumimplants AT amolvjanorkar citrusfruitbasedcalciumtitanateanodizationcoatingsontitaniumimplants AT michaeldroach citrusfruitbasedcalciumtitanateanodizationcoatingsontitaniumimplants |