The chemicalome profiling of Zishen Yuzhen Pill in vivo and its promoting effect on osteogenic differentiation of MC3T3-E1 cells

The chemicalome profiling of Zishen Yuzhen Pill in vivo and its promoting effect on osteogenic differentiation of MC3T3-E1 cells

Zishen Yuzhen Pill (ZYP) is a Chinese herbal product developed by Shenzhen TCM Hospital, which have been frequently used to treat osteoporosis (OP). This study aimed to determine the major chemical components of ZYP and its prototype compounds and metabolites in rat biological samples, as well as ex...

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Bibliographic Details
Main Authors: Juanjuan Cheng, Xinyue Meng, Daozheng Fang, Yong Zhu, Zhihao Liu, Xinyue Li, Ke Jie, Shiying Huang, Huilin Li, Shangbin Zhang, Jihang Chen, Jianping Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Analytical Science
Subjects:
Zishen Yuzhen Pill
UPLC-QTOF/MS
chemical characterization
osteoporosis
MC3T3-E1 cells
Online Access:https://www.frontiersin.org/articles/10.3389/frans.2025.1533486/full
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