Primary leptomeningeal melanocytosis: A case report with an autopsy diagnosis
Introduction. Primary melanocytosis of the leptomeninges is a rare tumor, most likely originating from the melanocytes in the leptomeninges. The average survival is only about 5 months. Case report. A 61- years-old woman presented with headache, amaurosis and hallucinations lasted for two months,...
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| Format: | Article |
| Language: | English |
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Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade
2012-01-01
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| Series: | Vojnosanitetski Pregled |
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| Online Access: | http://www.doiserbia.nb.rs/img/doi/0042-8450/2012/0042-84501207631Z.pdf |
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| author | Živković Nikola Mihailović Dragan Mijović Žaklina Jovičić-Milentijević Maja |
| author_facet | Živković Nikola Mihailović Dragan Mijović Žaklina Jovičić-Milentijević Maja |
| author_sort | Živković Nikola |
| collection | DOAJ |
| description | Introduction. Primary melanocytosis of the leptomeninges is a rare tumor, most likely originating from the melanocytes in the leptomeninges. The average survival is only about 5 months. Case report. A 61- years-old woman presented with headache, amaurosis and hallucinations lasted for two months, and she had been treated at the Clinic for Psychiatry and Clinic for Infectious Diseases. The cerebrospinal fluid analysis showed a lower level of glucose and a higher level of proteins. Small shaded areas of basal leptomeninges and hydrocephalus were found by computed tomography and magnetic resonance imaging. The autopsy showed a dark brown mass on basal leptomeninges with blurred boundaries. No pigmented skin lesions were found. Histopathological analysis revealed a primary leptomeningeal melanocytosis. Conclusion. Primary leptomeningeal melanocytosis is a rare tumor, difficult to diagnose. This case is being presented for its specificity, since this diagnosis is not frequently seen in practice. |
| format | Article |
| id | doaj-art-c62fbd1ca8e341f7933c167e54097486 |
| institution | DOAJ |
| issn | 0042-8450 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade |
| record_format | Article |
| series | Vojnosanitetski Pregled |
| spelling | doaj-art-c62fbd1ca8e341f7933c167e540974862025-08-20T03:22:43ZengMinistry of Defence of the Republic of Serbia, University of Defence, BelgradeVojnosanitetski Pregled0042-84502012-01-0169763163410.2298/VSP1207631ZPrimary leptomeningeal melanocytosis: A case report with an autopsy diagnosisŽivković NikolaMihailović DraganMijović ŽaklinaJovičić-Milentijević MajaIntroduction. Primary melanocytosis of the leptomeninges is a rare tumor, most likely originating from the melanocytes in the leptomeninges. The average survival is only about 5 months. Case report. A 61- years-old woman presented with headache, amaurosis and hallucinations lasted for two months, and she had been treated at the Clinic for Psychiatry and Clinic for Infectious Diseases. The cerebrospinal fluid analysis showed a lower level of glucose and a higher level of proteins. Small shaded areas of basal leptomeninges and hydrocephalus were found by computed tomography and magnetic resonance imaging. The autopsy showed a dark brown mass on basal leptomeninges with blurred boundaries. No pigmented skin lesions were found. Histopathological analysis revealed a primary leptomeningeal melanocytosis. Conclusion. Primary leptomeningeal melanocytosis is a rare tumor, difficult to diagnose. This case is being presented for its specificity, since this diagnosis is not frequently seen in practice.http://www.doiserbia.nb.rs/img/doi/0042-8450/2012/0042-84501207631Z.pdfmeningeal neoplasmsdiagnosistomography, x-raycomputedmagnetic resonance imagingautopsy6enzyme-linked immunosorbent assay |
| spellingShingle | Živković Nikola Mihailović Dragan Mijović Žaklina Jovičić-Milentijević Maja Primary leptomeningeal melanocytosis: A case report with an autopsy diagnosis Vojnosanitetski Pregled meningeal neoplasms diagnosis tomography, x-raycomputed magnetic resonance imaging autopsy 6enzyme-linked immunosorbent assay |
| title | Primary leptomeningeal melanocytosis: A case report with an autopsy diagnosis |
| title_full | Primary leptomeningeal melanocytosis: A case report with an autopsy diagnosis |
| title_fullStr | Primary leptomeningeal melanocytosis: A case report with an autopsy diagnosis |
| title_full_unstemmed | Primary leptomeningeal melanocytosis: A case report with an autopsy diagnosis |
| title_short | Primary leptomeningeal melanocytosis: A case report with an autopsy diagnosis |
| title_sort | primary leptomeningeal melanocytosis a case report with an autopsy diagnosis |
| topic | meningeal neoplasms diagnosis tomography, x-raycomputed magnetic resonance imaging autopsy 6enzyme-linked immunosorbent assay |
| url | http://www.doiserbia.nb.rs/img/doi/0042-8450/2012/0042-84501207631Z.pdf |
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