Sex disparities in hypertension prevalence, blood pressure trajectories and the effects of anti-hypertensive treatment
Introduction Sex differences in blood pressure (BP), hypertension and hypertension mediated cardiovascular complications have become an increasingly important focus of attention. This narrative review gives an overview of current studies on this topic, with the aim to provide a deeper understanding...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2024-12-01
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| Series: | Blood Pressure |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/08037051.2024.2365705 |
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| author | Esther M. C. Vriend Henrike Galenkamp Irene G. M. van Valkengoed Bert-Jan H. van den Born |
| author_facet | Esther M. C. Vriend Henrike Galenkamp Irene G. M. van Valkengoed Bert-Jan H. van den Born |
| author_sort | Esther M. C. Vriend |
| collection | DOAJ |
| description | Introduction Sex differences in blood pressure (BP), hypertension and hypertension mediated cardiovascular complications have become an increasingly important focus of attention. This narrative review gives an overview of current studies on this topic, with the aim to provide a deeper understanding of the sex-based disparities in hypertension with essential insights for refining prevention and management strategies for both men and women.Methods and results We searched Medline, Embase and the Cochrane libray on sex differences in BP-trajectories and hypertension prevalence. In the past decade various population-based studies have revealed substantial sex-disparities in BP-trajectories throughout life with women having a larger increase in hypertension prevalence after 30 years of age and a stronger association between BP and cardiovascular disease (CVD). In general, the effects of antihypertensive treatment appear to be consistent across sexes in different populations, although there remains uncertainty about differences in the efficacy of BP lowering drugs below 55 years of age.Conclusion The current uniform approach to the diagnosis and management of hypertension in both sexes neglects the distinctions in hypertension, while the differences underscore the need for sex-specific recommendations, particularly for younger individuals. A major limitation hampering insights into sex differences in BP-related outcomes is the lack of sex-stratified analyses or an adequate representation of women. Additional large-scale, longitudinal studies are imperative. |
| format | Article |
| id | doaj-art-c60fdfd3c223463b97102772cc24d162 |
| institution | DOAJ |
| issn | 0803-7051 1651-1999 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Blood Pressure |
| spelling | doaj-art-c60fdfd3c223463b97102772cc24d1622025-08-20T02:51:06ZengTaylor & Francis GroupBlood Pressure0803-70511651-19992024-12-0133110.1080/08037051.2024.2365705Sex disparities in hypertension prevalence, blood pressure trajectories and the effects of anti-hypertensive treatmentEsther M. C. Vriend0Henrike Galenkamp1Irene G. M. van Valkengoed2Bert-Jan H. van den Born3Department of Internal Medicine, Section Vascular Medicine, Amsterdam Cardiovascular Sciences, Amsterdam UMC, University of Amsterdam, Amsterdam, The NetherlandsDepartment of Public and Occupational Health, Amsterdam Public Health Research institute, Amsterdam UMC, University of Amsterdam, Amsterdam, The NetherlandsDepartment of Public and Occupational Health, Amsterdam Public Health Research institute, Amsterdam UMC, University of Amsterdam, Amsterdam, The NetherlandsDepartment of Internal Medicine, Section Vascular Medicine, Amsterdam Cardiovascular Sciences, Amsterdam UMC, University of Amsterdam, Amsterdam, The NetherlandsIntroduction Sex differences in blood pressure (BP), hypertension and hypertension mediated cardiovascular complications have become an increasingly important focus of attention. This narrative review gives an overview of current studies on this topic, with the aim to provide a deeper understanding of the sex-based disparities in hypertension with essential insights for refining prevention and management strategies for both men and women.Methods and results We searched Medline, Embase and the Cochrane libray on sex differences in BP-trajectories and hypertension prevalence. In the past decade various population-based studies have revealed substantial sex-disparities in BP-trajectories throughout life with women having a larger increase in hypertension prevalence after 30 years of age and a stronger association between BP and cardiovascular disease (CVD). In general, the effects of antihypertensive treatment appear to be consistent across sexes in different populations, although there remains uncertainty about differences in the efficacy of BP lowering drugs below 55 years of age.Conclusion The current uniform approach to the diagnosis and management of hypertension in both sexes neglects the distinctions in hypertension, while the differences underscore the need for sex-specific recommendations, particularly for younger individuals. A major limitation hampering insights into sex differences in BP-related outcomes is the lack of sex-stratified analyses or an adequate representation of women. Additional large-scale, longitudinal studies are imperative.https://www.tandfonline.com/doi/10.1080/08037051.2024.2365705Hypertensionblood pressuresexantihypertensive medicationcardiovascular disease |
| spellingShingle | Esther M. C. Vriend Henrike Galenkamp Irene G. M. van Valkengoed Bert-Jan H. van den Born Sex disparities in hypertension prevalence, blood pressure trajectories and the effects of anti-hypertensive treatment Blood Pressure Hypertension blood pressure sex antihypertensive medication cardiovascular disease |
| title | Sex disparities in hypertension prevalence, blood pressure trajectories and the effects of anti-hypertensive treatment |
| title_full | Sex disparities in hypertension prevalence, blood pressure trajectories and the effects of anti-hypertensive treatment |
| title_fullStr | Sex disparities in hypertension prevalence, blood pressure trajectories and the effects of anti-hypertensive treatment |
| title_full_unstemmed | Sex disparities in hypertension prevalence, blood pressure trajectories and the effects of anti-hypertensive treatment |
| title_short | Sex disparities in hypertension prevalence, blood pressure trajectories and the effects of anti-hypertensive treatment |
| title_sort | sex disparities in hypertension prevalence blood pressure trajectories and the effects of anti hypertensive treatment |
| topic | Hypertension blood pressure sex antihypertensive medication cardiovascular disease |
| url | https://www.tandfonline.com/doi/10.1080/08037051.2024.2365705 |
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