HIF-1α Regulated WTAP Overexpression Promoting the Warburg Effect of Ovarian Cancer by m6A-Dependent Manner
N6-methyladenosine (m6A) RNA methylation has been determined to execute crucial functions in tumorigenesis and cancer development. WT1-associated protein (WTAP) has an important “writer” role in m6A modification, and it is also a nuclear protein that colocalizes with splicing factors and plays a cri...
Saved in:
| Main Authors: | Yuanyuan Lyu, Yilin Zhang, Yuhan Wang, Yonghong Luo, Huafeng Ding, Peiling Li, Guantai Ni |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2022-01-01
|
| Series: | Journal of Immunology Research |
| Online Access: | http://dx.doi.org/10.1155/2022/6130806 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
WTAP participates in the DNA damage response via an m6A-FOXM1-dependent manner in hepatocellular carcinoma
by: Nan Huang, et al.
Published: (2025-08-01) -
HIF-2α not HIF-1α overexpression confers poor prognosis in non–small cell lung cancer
by: Zhao-Jia Gao, et al.
Published: (2017-06-01) -
Overexpression of MAFG-AS1 in ovarian cancer promotes glucose metabolism reprogramming and malignant biological behavior of ovarian cancer cells by regulating HIF-1α
by: Liu Jia, et al.
Published: (2025-05-01) -
Transcription factor ONECUT3 regulates HDAC6/HIF-1α activity to promote the Warburg effect and tumor growth in colorectal cancer
by: Ruixue Huo, et al.
Published: (2025-03-01) -
The α-globin super-enhancer acts in an orientation-dependent manner
by: Mira T. Kassouf, et al.
Published: (2025-01-01)