Patent foramen ovale in young stroke patients: diagnostic challenge and a new approach to the secondary prevention (a case report and review of literature)
Patent foramen ovale (PFO) occurs in about 25% of healthy adults, however, it is significantly more common among patients with cryptogenic stroke. Although PFO might be a direct cause of ischemia, it is often an accidental finding in stroke patients. In most cases, cryptogenic stroke with PFO is ju...
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| Format: | Article |
| Language: | English |
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Vilnius University Press
2018-06-01
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| Series: | Neurologijos seminarai |
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| Online Access: | https://www.journals.vu.lt/neurologijos_seminarai/article/view/27843 |
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| _version_ | 1832593087790055424 |
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| author | I. Beržanskytė J. Valaikienė D. Jatužis |
| author_facet | I. Beržanskytė J. Valaikienė D. Jatužis |
| author_sort | I. Beržanskytė |
| collection | DOAJ |
| description |
Patent foramen ovale (PFO) occurs in about 25% of healthy adults, however, it is significantly more common among patients with cryptogenic stroke. Although PFO might be a direct cause of ischemia, it is often an accidental finding in stroke patients. In most cases, cryptogenic stroke with PFO is just a presumed diagnosis as it is difficult to prove PFO as etiological factor. Randomized trials and meta-analysis have showed controversial results in searching for the most effective prevention of cryptogenic stroke with PFO recurrence in the last six years. Nevertheless, currently available data suggests that PFO closure is superior to medical therapy. Two problems remain in clinical settings: identification of patients who would benefit from PFO closure most and the exact indications for intervention. In this article we present a clinical case and review literature examining diagnostic and secondary prevention of cryptogenic stroke with PFO.
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| format | Article |
| id | doaj-art-c6097d96943b45408fe1787b3cf265b8 |
| institution | Kabale University |
| issn | 1392-3064 2424-5917 |
| language | English |
| publishDate | 2018-06-01 |
| publisher | Vilnius University Press |
| record_format | Article |
| series | Neurologijos seminarai |
| spelling | doaj-art-c6097d96943b45408fe1787b3cf265b82025-01-20T18:23:14ZengVilnius University PressNeurologijos seminarai1392-30642424-59172018-06-01222(76)10.29014/ns.2018.17Patent foramen ovale in young stroke patients: diagnostic challenge and a new approach to the secondary prevention (a case report and review of literature)I. Beržanskytė 0J. Valaikienė 1D. Jatužis 2Vilnius University, LithuaniaVilnius University, LithuaniaVilnius University, Lithuania Patent foramen ovale (PFO) occurs in about 25% of healthy adults, however, it is significantly more common among patients with cryptogenic stroke. Although PFO might be a direct cause of ischemia, it is often an accidental finding in stroke patients. In most cases, cryptogenic stroke with PFO is just a presumed diagnosis as it is difficult to prove PFO as etiological factor. Randomized trials and meta-analysis have showed controversial results in searching for the most effective prevention of cryptogenic stroke with PFO recurrence in the last six years. Nevertheless, currently available data suggests that PFO closure is superior to medical therapy. Two problems remain in clinical settings: identification of patients who would benefit from PFO closure most and the exact indications for intervention. In this article we present a clinical case and review literature examining diagnostic and secondary prevention of cryptogenic stroke with PFO. https://www.journals.vu.lt/neurologijos_seminarai/article/view/27843patent foramen ovalecryptogenic strokeembolic stroke of undetermined sourceparadoxical embolization |
| spellingShingle | I. Beržanskytė J. Valaikienė D. Jatužis Patent foramen ovale in young stroke patients: diagnostic challenge and a new approach to the secondary prevention (a case report and review of literature) Neurologijos seminarai patent foramen ovale cryptogenic stroke embolic stroke of undetermined source paradoxical embolization |
| title | Patent foramen ovale in young stroke patients: diagnostic challenge and a new approach to the secondary prevention (a case report and review of literature) |
| title_full | Patent foramen ovale in young stroke patients: diagnostic challenge and a new approach to the secondary prevention (a case report and review of literature) |
| title_fullStr | Patent foramen ovale in young stroke patients: diagnostic challenge and a new approach to the secondary prevention (a case report and review of literature) |
| title_full_unstemmed | Patent foramen ovale in young stroke patients: diagnostic challenge and a new approach to the secondary prevention (a case report and review of literature) |
| title_short | Patent foramen ovale in young stroke patients: diagnostic challenge and a new approach to the secondary prevention (a case report and review of literature) |
| title_sort | patent foramen ovale in young stroke patients diagnostic challenge and a new approach to the secondary prevention a case report and review of literature |
| topic | patent foramen ovale cryptogenic stroke embolic stroke of undetermined source paradoxical embolization |
| url | https://www.journals.vu.lt/neurologijos_seminarai/article/view/27843 |
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