Electroanalysis Advances in Pharmaceutical Sciences: Applications and Challenges Ahead
Electroanalysis has emerged as a critical tool in the pharmaceutical industry, offering versatile and sensitive methods for drug analysis. This review explores the principles, techniques, and applications of electroanalysis in pharmaceuticals, emphasizing its role in drug development, quality assura...
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| Language: | English |
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MDPI AG
2025-03-01
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| Series: | Analytica |
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| Online Access: | https://www.mdpi.com/2673-4532/6/2/12 |
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| author | Ram Kumar Sushant Salwan Pawan Kumar Nisha Bansal Bhupinder Kumar |
| author_facet | Ram Kumar Sushant Salwan Pawan Kumar Nisha Bansal Bhupinder Kumar |
| author_sort | Ram Kumar |
| collection | DOAJ |
| description | Electroanalysis has emerged as a critical tool in the pharmaceutical industry, offering versatile and sensitive methods for drug analysis. This review explores the principles, techniques, and applications of electroanalysis in pharmaceuticals, emphasizing its role in drug development, quality assurance, pharmacokinetics, and environmental monitoring. Key electroanalytical methods, including voltammetry, potentiometry, and amperometry, are detailed along with their practical applications, such as detecting active pharmaceutical ingredients, monitoring drug metabolites, and ensuring product stability. Innovations in electrode materials and biosensors have enhanced their sensitivity and specificity, paving the way for advanced drug screening and therapeutic monitoring. Challenges like electrode fouling, selectivity issues, and regulatory constraints are discussed, along with strategies to overcome them. Future trends highlight the integration of nanotechnology, AI, and portable sensors to facilitate real-time analysis and personalized medicine. These advancements position electroanalysis as an indispensable component of modern pharmaceutical research and healthcare. Future perspectives emphasize the integration of nanotechnology and artificial intelligence (AI) to optimize experimental processes and data interpretation. This study also predicts the increased adoption of lab-on-a-chip systems and bioelectrochemical sensors to meet the growing demand for precision medicine and sustainable pharmaceutical practices. These advancements position electroanalysis as a cornerstone of pharmaceutical research, paving the way for more efficient drug development, improved patient outcomes and better environmental management. This comprehensive review underscores the transformative potential of electroanalysis in addressing the evolving challenges of the pharmaceutical industry and provides a foundation for future innovations. This review does not explicitly define the timeframe for the considered advancements. However, it discusses recent technological developments, including innovations in nanostructured electrodes, microfluidic integration, and AI-driven data analysis, indicating a focus on advancements primarily from the last few years, i.e., from 2020 to 2025. |
| format | Article |
| id | doaj-art-c605d64db6f34657882737e542ca146f |
| institution | OA Journals |
| issn | 2673-4532 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Analytica |
| spelling | doaj-art-c605d64db6f34657882737e542ca146f2025-08-20T02:24:25ZengMDPI AGAnalytica2673-45322025-03-01621210.3390/analytica6020012Electroanalysis Advances in Pharmaceutical Sciences: Applications and Challenges AheadRam Kumar0Sushant Salwan1Pawan Kumar2Nisha Bansal3Bhupinder Kumar4Chitkara College of Pharmacy, Chitkara University, Rajpura 140401, Punjab, IndiaFaculty of Pharmaceutical Sciences, The ICFAI University, Baddi 174103, Himachal Pradesh, IndiaDepartment of Pharmaceutical Sciences and Technology, Maharaja Ranjit Singh Punjab Technical University, Bathinda 151001, Punjab, IndiaGramothan Vidyapeeth Home Science Girls PG College, Sangaria 335063, Rajasthan, IndiaDepartment of Pharmaceutical Sciences, HNB Garhwal University, Chauras Campus, Srinagar 246174, Uttarakhand, IndiaElectroanalysis has emerged as a critical tool in the pharmaceutical industry, offering versatile and sensitive methods for drug analysis. This review explores the principles, techniques, and applications of electroanalysis in pharmaceuticals, emphasizing its role in drug development, quality assurance, pharmacokinetics, and environmental monitoring. Key electroanalytical methods, including voltammetry, potentiometry, and amperometry, are detailed along with their practical applications, such as detecting active pharmaceutical ingredients, monitoring drug metabolites, and ensuring product stability. Innovations in electrode materials and biosensors have enhanced their sensitivity and specificity, paving the way for advanced drug screening and therapeutic monitoring. Challenges like electrode fouling, selectivity issues, and regulatory constraints are discussed, along with strategies to overcome them. Future trends highlight the integration of nanotechnology, AI, and portable sensors to facilitate real-time analysis and personalized medicine. These advancements position electroanalysis as an indispensable component of modern pharmaceutical research and healthcare. Future perspectives emphasize the integration of nanotechnology and artificial intelligence (AI) to optimize experimental processes and data interpretation. This study also predicts the increased adoption of lab-on-a-chip systems and bioelectrochemical sensors to meet the growing demand for precision medicine and sustainable pharmaceutical practices. These advancements position electroanalysis as a cornerstone of pharmaceutical research, paving the way for more efficient drug development, improved patient outcomes and better environmental management. This comprehensive review underscores the transformative potential of electroanalysis in addressing the evolving challenges of the pharmaceutical industry and provides a foundation for future innovations. This review does not explicitly define the timeframe for the considered advancements. However, it discusses recent technological developments, including innovations in nanostructured electrodes, microfluidic integration, and AI-driven data analysis, indicating a focus on advancements primarily from the last few years, i.e., from 2020 to 2025.https://www.mdpi.com/2673-4532/6/2/12analytical methodselectroanalytical methodspharmaceutical analysis |
| spellingShingle | Ram Kumar Sushant Salwan Pawan Kumar Nisha Bansal Bhupinder Kumar Electroanalysis Advances in Pharmaceutical Sciences: Applications and Challenges Ahead Analytica analytical methods electroanalytical methods pharmaceutical analysis |
| title | Electroanalysis Advances in Pharmaceutical Sciences: Applications and Challenges Ahead |
| title_full | Electroanalysis Advances in Pharmaceutical Sciences: Applications and Challenges Ahead |
| title_fullStr | Electroanalysis Advances in Pharmaceutical Sciences: Applications and Challenges Ahead |
| title_full_unstemmed | Electroanalysis Advances in Pharmaceutical Sciences: Applications and Challenges Ahead |
| title_short | Electroanalysis Advances in Pharmaceutical Sciences: Applications and Challenges Ahead |
| title_sort | electroanalysis advances in pharmaceutical sciences applications and challenges ahead |
| topic | analytical methods electroanalytical methods pharmaceutical analysis |
| url | https://www.mdpi.com/2673-4532/6/2/12 |
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