Matrix-induced nuclear remodeling and mechano-therapeutics
Summary: The extracellular matrix (ECM) provides structural support and mechanical cues that profoundly influence cellular behavior via nuclear mechanotransduction. This review discusses how ECM biophysical properties, including stiffness, topology, and spatial confinement, regulate nuclear mechanic...
Saved in:
| Main Authors: | Jung-Hwan Lee, Yeo Gyun Yun, Hae-Won Kim |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-09-01
|
| Series: | Cell Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124725009477 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
C9ORF72 poly-PR induces TDP-43 nuclear condensation via NEAT1 and is modulated by HSP70 activity
by: Diksha Agnihotri, et al.
Published: (2025-01-01) -
Starvation activates ECM-remodeling gene transcription and putative enhancers in fibroblasts despite inducing quiescence
by: Stefano Secchia, et al.
Published: (2025-07-01) -
Mitochondrial GCN5L1 coordinates with YME1L and MICOS to remodel mitochondrial cristae in white adipocytes and modulate obesity
by: Juan Xu, et al.
Published: (2025-05-01) -
Spatial organizations of heterochromatin underpin nuclear structural integrity of ventricular cardiomyocytes against mechanical stress
by: Keita Fujiwara, et al.
Published: (2024-12-01) -
Mechanobiological mechanism of cyclic stretch-induced cell columnarization
by: Lun-Wei Lee, et al.
Published: (2025-05-01)