Natural product Erianin: mitigating FOLFOX toxicity and enhancing against colorectal cancer

Natural product Erianin: mitigating FOLFOX toxicity and enhancing against colorectal cancer

IntroductionColorectal cancer (CRC) is a prevalent malignant tumor of the digestive tract. The FOLFOX regimen (oxaliplatin + calcium folinate + 5-fluorouracil) serves as the primary treatment for advanced CRC clinically, yet its application is significantly limited by substantial toxic side effects....

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Bibliographic Details
Main Authors: Fuqin Yang, Zeqiao Li, Haishan Zhang, Mingxiao Zhang, Zhenwei He, Xiaoqin Zheng, Yingru Zhu, Pei Long, Ruirui Ding, Zhengbin Lin, Lijuan Deng
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Chemistry
Subjects:
Erianin
FOLFOX regimen
colorectal cancer
toxicity reduction
efficacy enhancement
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2025.1650197/full
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