Diagnostic challenge of an untypical cutaneous drug reaction from modafinil

Key Clinical Message Modafinil used for narcolepsy caused an atypical adverse reaction, as itchy acneiform lesions, subcutaneous nodules and superficial skin wounds after 2 years of use. After extensive examinations for 5 years, modafinil was discontinued, and the healing process began in 3 weeks wi...

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Main Authors: Rauno J. Harvima, Tarja Heiskanen‐Kosma, Miika Arvonen, Ilkka T. Harvima
Format: Article
Language:English
Published: Wiley 2024-09-01
Series:Clinical Case Reports
Subjects:
Online Access:https://doi.org/10.1002/ccr3.9166
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author Rauno J. Harvima
Tarja Heiskanen‐Kosma
Miika Arvonen
Ilkka T. Harvima
author_facet Rauno J. Harvima
Tarja Heiskanen‐Kosma
Miika Arvonen
Ilkka T. Harvima
author_sort Rauno J. Harvima
collection DOAJ
description Key Clinical Message Modafinil used for narcolepsy caused an atypical adverse reaction, as itchy acneiform lesions, subcutaneous nodules and superficial skin wounds after 2 years of use. After extensive examinations for 5 years, modafinil was discontinued, and the healing process began in 3 weeks with completion in 1.5 years.
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publishDate 2024-09-01
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spelling doaj-art-c5e64b72bba04c549fea5fbcdd4d58e02025-08-20T02:50:22ZengWileyClinical Case Reports2050-09042024-09-01129n/an/a10.1002/ccr3.9166Diagnostic challenge of an untypical cutaneous drug reaction from modafinilRauno J. Harvima0Tarja Heiskanen‐Kosma1Miika Arvonen2Ilkka T. Harvima3Department of Dermatology Kuopio University Hospital and University of Eastern Finland Kuopio FinlandDepartment of Pediatrics Kuopio University Hospital Kuopio FinlandDepartment of Pediatrics Kuopio University Hospital Kuopio FinlandDepartment of Dermatology Kuopio University Hospital and University of Eastern Finland Kuopio FinlandKey Clinical Message Modafinil used for narcolepsy caused an atypical adverse reaction, as itchy acneiform lesions, subcutaneous nodules and superficial skin wounds after 2 years of use. After extensive examinations for 5 years, modafinil was discontinued, and the healing process began in 3 weeks with completion in 1.5 years.https://doi.org/10.1002/ccr3.9166modafinilrare presentationskin adverse reactiontreatment
spellingShingle Rauno J. Harvima
Tarja Heiskanen‐Kosma
Miika Arvonen
Ilkka T. Harvima
Diagnostic challenge of an untypical cutaneous drug reaction from modafinil
Clinical Case Reports
modafinil
rare presentation
skin adverse reaction
treatment
title Diagnostic challenge of an untypical cutaneous drug reaction from modafinil
title_full Diagnostic challenge of an untypical cutaneous drug reaction from modafinil
title_fullStr Diagnostic challenge of an untypical cutaneous drug reaction from modafinil
title_full_unstemmed Diagnostic challenge of an untypical cutaneous drug reaction from modafinil
title_short Diagnostic challenge of an untypical cutaneous drug reaction from modafinil
title_sort diagnostic challenge of an untypical cutaneous drug reaction from modafinil
topic modafinil
rare presentation
skin adverse reaction
treatment
url https://doi.org/10.1002/ccr3.9166
work_keys_str_mv AT raunojharvima diagnosticchallengeofanuntypicalcutaneousdrugreactionfrommodafinil
AT tarjaheiskanenkosma diagnosticchallengeofanuntypicalcutaneousdrugreactionfrommodafinil
AT miikaarvonen diagnosticchallengeofanuntypicalcutaneousdrugreactionfrommodafinil
AT ilkkatharvima diagnosticchallengeofanuntypicalcutaneousdrugreactionfrommodafinil