Indium-111 Capromab Pendetide (ProstaScint®) Demonstrates Renal Cell Carcinoma and Aortocaval Nodal Metastases from Prostate Adenocarcinoma
A 62-year-old male with a history of radical prostatectomy for a Gleason 9 (4 + 5) pT3N0Mx prostate cancer presented with rising prostate-specific antigen of 9.0 ng/dl. A contrast-enhanced computerized tomography (CT) revealed an enhancing left upper pole renal mass and aortocaval lymph nodes. Indiu...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Thieme Medical and Scientific Publishers Pvt. Ltd.
2015-07-01
|
| Series: | World Journal of Nuclear Medicine |
| Subjects: | |
| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.4103/1450-1147.163259 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849324721567432704 |
|---|---|
| author | Tanvir Rizvi Chunli Deng Patrice Rehm |
| author_facet | Tanvir Rizvi Chunli Deng Patrice Rehm |
| author_sort | Tanvir Rizvi |
| collection | DOAJ |
| description | A 62-year-old male with a history of radical prostatectomy for a Gleason 9 (4 + 5) pT3N0Mx prostate cancer presented with rising prostate-specific antigen of 9.0 ng/dl. A contrast-enhanced computerized tomography (CT) revealed an enhancing left upper pole renal mass and aortocaval lymph nodes. Indium (In)-111 Capromab Pendetide (ProstaScint ® ) single-photon emission computerized tomography-CT showed abnormal increased uptake in left renal mass and aortocaval lymph nodes with no uptake in the prostate bed or pelvic lymph nodes. He underwent left radical nephrectomy and dissection of aortocaval lymph nodes. Pathology showed renal clear cell carcinoma and metastatic prostate adenocarcinoma involving aortocaval lymph nodes. Our case demonstrates a rare combination of two different malignancies, prostate cancer and clear cell renal cell cancer, showing In-111 ProstaScint ® uptake. Though ProstaScint ® uptake in renal cell carcinoma and in metastatic aortocaval lymph nodes from prostate cancer may be seen in clinical practice, this combination has not been reported previously. |
| format | Article |
| id | doaj-art-c5ddbcc4090541eea2a86caf60beaa60 |
| institution | Kabale University |
| issn | 1450-1147 1607-3312 |
| language | English |
| publishDate | 2015-07-01 |
| publisher | Thieme Medical and Scientific Publishers Pvt. Ltd. |
| record_format | Article |
| series | World Journal of Nuclear Medicine |
| spelling | doaj-art-c5ddbcc4090541eea2a86caf60beaa602025-08-20T03:48:36ZengThieme Medical and Scientific Publishers Pvt. Ltd.World Journal of Nuclear Medicine1450-11471607-33122015-07-01140320921110.4103/1450-1147.163259Indium-111 Capromab Pendetide (ProstaScint®) Demonstrates Renal Cell Carcinoma and Aortocaval Nodal Metastases from Prostate AdenocarcinomaTanvir Rizvi0Chunli Deng1Patrice Rehm2Department of Radiology and Medical Imaging, University of Virginia Health System, Charlottesville, VA 22908Department of Radiology, Cincinnati VA Health System, Cincinnati, OH 45220, USADepartment of Radiology and Medical Imaging, University of Virginia Health System, Charlottesville, VA 22908A 62-year-old male with a history of radical prostatectomy for a Gleason 9 (4 + 5) pT3N0Mx prostate cancer presented with rising prostate-specific antigen of 9.0 ng/dl. A contrast-enhanced computerized tomography (CT) revealed an enhancing left upper pole renal mass and aortocaval lymph nodes. Indium (In)-111 Capromab Pendetide (ProstaScint ® ) single-photon emission computerized tomography-CT showed abnormal increased uptake in left renal mass and aortocaval lymph nodes with no uptake in the prostate bed or pelvic lymph nodes. He underwent left radical nephrectomy and dissection of aortocaval lymph nodes. Pathology showed renal clear cell carcinoma and metastatic prostate adenocarcinoma involving aortocaval lymph nodes. Our case demonstrates a rare combination of two different malignancies, prostate cancer and clear cell renal cell cancer, showing In-111 ProstaScint ® uptake. Though ProstaScint ® uptake in renal cell carcinoma and in metastatic aortocaval lymph nodes from prostate cancer may be seen in clinical practice, this combination has not been reported previously.http://www.thieme-connect.de/DOI/DOI?10.4103/1450-1147.163259clear cell renal carcinomaprostascint ® scanprostate cancer |
| spellingShingle | Tanvir Rizvi Chunli Deng Patrice Rehm Indium-111 Capromab Pendetide (ProstaScint®) Demonstrates Renal Cell Carcinoma and Aortocaval Nodal Metastases from Prostate Adenocarcinoma World Journal of Nuclear Medicine clear cell renal carcinoma prostascint ® scan prostate cancer |
| title | Indium-111 Capromab Pendetide (ProstaScint®) Demonstrates Renal Cell Carcinoma and Aortocaval Nodal Metastases from Prostate Adenocarcinoma |
| title_full | Indium-111 Capromab Pendetide (ProstaScint®) Demonstrates Renal Cell Carcinoma and Aortocaval Nodal Metastases from Prostate Adenocarcinoma |
| title_fullStr | Indium-111 Capromab Pendetide (ProstaScint®) Demonstrates Renal Cell Carcinoma and Aortocaval Nodal Metastases from Prostate Adenocarcinoma |
| title_full_unstemmed | Indium-111 Capromab Pendetide (ProstaScint®) Demonstrates Renal Cell Carcinoma and Aortocaval Nodal Metastases from Prostate Adenocarcinoma |
| title_short | Indium-111 Capromab Pendetide (ProstaScint®) Demonstrates Renal Cell Carcinoma and Aortocaval Nodal Metastases from Prostate Adenocarcinoma |
| title_sort | indium 111 capromab pendetide prostascint r demonstrates renal cell carcinoma and aortocaval nodal metastases from prostate adenocarcinoma |
| topic | clear cell renal carcinoma prostascint ® scan prostate cancer |
| url | http://www.thieme-connect.de/DOI/DOI?10.4103/1450-1147.163259 |
| work_keys_str_mv | AT tanvirrizvi indium111capromabpendetideprostascintdemonstratesrenalcellcarcinomaandaortocavalnodalmetastasesfromprostateadenocarcinoma AT chunlideng indium111capromabpendetideprostascintdemonstratesrenalcellcarcinomaandaortocavalnodalmetastasesfromprostateadenocarcinoma AT patricerehm indium111capromabpendetideprostascintdemonstratesrenalcellcarcinomaandaortocavalnodalmetastasesfromprostateadenocarcinoma |