Characterization of high protein soybean using mass spectrometry based proteomic and metabolomic analyses

We have created several high protein (HPBL) and low protein breeding lines (LPBL) by crossing between NC-Raleigh and PI407228. The NC-Raleigh is a low protein cultivar widely grown in North Carolina with excellent yield potential and a high protein wild soybean (Glycine soja) with low yield. We anal...

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Main Authors: Nazrul Islam, Qijian Song, Savithiry Natarajan
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Journal of Agriculture and Food Research
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Online Access:http://www.sciencedirect.com/science/article/pii/S2666154324004927
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author Nazrul Islam
Qijian Song
Savithiry Natarajan
author_facet Nazrul Islam
Qijian Song
Savithiry Natarajan
author_sort Nazrul Islam
collection DOAJ
description We have created several high protein (HPBL) and low protein breeding lines (LPBL) by crossing between NC-Raleigh and PI407228. The NC-Raleigh is a low protein cultivar widely grown in North Carolina with excellent yield potential and a high protein wild soybean (Glycine soja) with low yield. We analyzed the F6 generation of this cross for protein and oil compositions using near-infrared spectroscopy (NIR). Two soybean lines HPBL and LPBL were selected for biochemical analysis using mass spectrometry-based proteomic and metabolomic techniques. We identified 4538 proteins and 267 metabolites in these lines. The HPBL showed the enrichment of proteins associated with protein synthesis, processing, and storage in addition to higher content of primary and secondary metabolites. The mapping of metabolites on the global metabolic pathways revealed the increased protein content in the HPBL that may have resulted from increased arginine content routed from citrulline-argininosuccinic acid. This information will be useful for breeders and biotechnologists to produce a value-added soybean trait.
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publishDate 2024-12-01
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spelling doaj-art-c5d7cfa0284b4ef88cdb1eb35a66cdeb2025-08-20T02:49:04ZengElsevierJournal of Agriculture and Food Research2666-15432024-12-011810145510.1016/j.jafr.2024.101455Characterization of high protein soybean using mass spectrometry based proteomic and metabolomic analysesNazrul Islam0Qijian Song1Savithiry Natarajan2Soybean Genomics and Improvement Laboratory, USDA-ARS, Beltsville, MD, 20705, USASoybean Genomics and Improvement Laboratory, USDA-ARS, Beltsville, MD, 20705, USACorresponding author.; Soybean Genomics and Improvement Laboratory, USDA-ARS, Beltsville, MD, 20705, USAWe have created several high protein (HPBL) and low protein breeding lines (LPBL) by crossing between NC-Raleigh and PI407228. The NC-Raleigh is a low protein cultivar widely grown in North Carolina with excellent yield potential and a high protein wild soybean (Glycine soja) with low yield. We analyzed the F6 generation of this cross for protein and oil compositions using near-infrared spectroscopy (NIR). Two soybean lines HPBL and LPBL were selected for biochemical analysis using mass spectrometry-based proteomic and metabolomic techniques. We identified 4538 proteins and 267 metabolites in these lines. The HPBL showed the enrichment of proteins associated with protein synthesis, processing, and storage in addition to higher content of primary and secondary metabolites. The mapping of metabolites on the global metabolic pathways revealed the increased protein content in the HPBL that may have resulted from increased arginine content routed from citrulline-argininosuccinic acid. This information will be useful for breeders and biotechnologists to produce a value-added soybean trait.http://www.sciencedirect.com/science/article/pii/S2666154324004927SoybeanProteomicsMetabolomicsMass spectrometrySeedPathways
spellingShingle Nazrul Islam
Qijian Song
Savithiry Natarajan
Characterization of high protein soybean using mass spectrometry based proteomic and metabolomic analyses
Journal of Agriculture and Food Research
Soybean
Proteomics
Metabolomics
Mass spectrometry
Seed
Pathways
title Characterization of high protein soybean using mass spectrometry based proteomic and metabolomic analyses
title_full Characterization of high protein soybean using mass spectrometry based proteomic and metabolomic analyses
title_fullStr Characterization of high protein soybean using mass spectrometry based proteomic and metabolomic analyses
title_full_unstemmed Characterization of high protein soybean using mass spectrometry based proteomic and metabolomic analyses
title_short Characterization of high protein soybean using mass spectrometry based proteomic and metabolomic analyses
title_sort characterization of high protein soybean using mass spectrometry based proteomic and metabolomic analyses
topic Soybean
Proteomics
Metabolomics
Mass spectrometry
Seed
Pathways
url http://www.sciencedirect.com/science/article/pii/S2666154324004927
work_keys_str_mv AT nazrulislam characterizationofhighproteinsoybeanusingmassspectrometrybasedproteomicandmetabolomicanalyses
AT qijiansong characterizationofhighproteinsoybeanusingmassspectrometrybasedproteomicandmetabolomicanalyses
AT savithirynatarajan characterizationofhighproteinsoybeanusingmassspectrometrybasedproteomicandmetabolomicanalyses