Takayasu’s arteritis with involvement of small cutaneous vessels - with regard to a clinical case
Takayasu’s arteritis (TA) is a vasculitis that affects large vessels. Rarely, microcirculation is involved, sometimes with cutaneous manifestations. Inflammation of small vessels of the skin can present as erythema nodosum-like lesions and granulomatous cutaneous vasculitis, among others. We describ...
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Sociedade Portuguesa de Dermatologia e Venereologia
2025-04-01
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| Series: | Revista da Sociedade Portuguesa de Dermatologia e Venereologia |
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| Online Access: | https://www.portuguesejournalofdermatology.com/frame_eng.php?id=199 |
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| author | Ma. Cristina Fialho Sara Castro Sara Dias Ricardo Veiga Ana Ferreirinha Emanuel Marques Cândida Fernandes |
| author_facet | Ma. Cristina Fialho Sara Castro Sara Dias Ricardo Veiga Ana Ferreirinha Emanuel Marques Cândida Fernandes |
| author_sort | Ma. Cristina Fialho |
| collection | DOAJ |
| description | Takayasu’s arteritis (TA) is a vasculitis that affects large vessels. Rarely, microcirculation is involved, sometimes with cutaneous manifestations. Inflammation of small vessels of the skin can present as erythema nodosum-like lesions and granulomatous cutaneous vasculitis, among others. We describe the case of a 29-year-old woman with a diagnosis of TA confirmed by angio-CT. She was referred to a dermatology appointment due to a skin condition characterized by centimetric, erythematous, painful, and nonulcerated nodules on the soles and inner edges of the feet. Clinical and analytical criteria of active disease were met, despite implemented corticotherapy. Cutaneous biopsy showed panniculitis and leukocytoclastic vasculitis. Autoimmune vasculitis and cryoglobulinemia panels were negative. Erythema nodosum-like subcutaneous nodules have been described in TA, possibly preceding other disease manifestations or as markers of disease activity. An early correlation with constitutional and cardiovascular symptoms may lead to earlier diagnosis and prompt control of disease activity.Takayasu’s arteritis (TA) is a vasculitis that affects large vessels. Rarely, microcirculation is involved, sometimes with cutaneous manifestations. Inflammation of small vessels of the skin can present as erythema nodosum-like lesions and granulomatous cutaneous vasculitis, among others. We describe the case of a 29-year-old woman with a diagnosis of TA confirmed by angio-CT. She was referred to a dermatology appointment due to a skin condition characterized by centimetric, erythematous, painful, and nonulcerated nodules on the soles and inner edges of the feet. Clinical and analytical criteria of active disease were met, despite implemented corticotherapy. Cutaneous biopsy showed panniculitis and leukocytoclastic vasculitis. Autoimmune vasculitis and cryoglobulinemia panels were negative. Erythema nodosum-like subcutaneous nodules have been described in TA, possibly preceding other disease manifestations or as markers of disease activity. An early correlation with constitutional and cardiovascular symptoms may lead to earlier diagnosis and prompt control of disease activity.
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| format | Article |
| id | doaj-art-c5cb0abb65a54c07af1135c688e8055c |
| institution | DOAJ |
| issn | 2182-2395 2182-2409 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Sociedade Portuguesa de Dermatologia e Venereologia |
| record_format | Article |
| series | Revista da Sociedade Portuguesa de Dermatologia e Venereologia |
| spelling | doaj-art-c5cb0abb65a54c07af1135c688e8055c2025-08-20T02:39:48ZengSociedade Portuguesa de Dermatologia e VenereologiaRevista da Sociedade Portuguesa de Dermatologia e Venereologia2182-23952182-24092025-04-01832Takayasu’s arteritis with involvement of small cutaneous vessels - with regard to a clinical caseMa. Cristina Fialho0Sara Castro1Sara Dias2Ricardo Veiga3Ana Ferreirinha4Emanuel Marques5Cândida Fernandes6Department of Dermatology and Venereology, Hospital de Santo António dos Capuchos, Unidade Local de Saúde de São José, Lisbon, PortugalInternal Medicine Department, Hospital Curry Cabral, Unidade Local de Saúde de São José, Lisbon, PortugalInternal Medicine Department, Hospital Curry Cabral, Unidade Local de Saúde de São José, Lisbon, PortugalDermatology and Venereology Department, Hospital de Santo António dos Capuchos, Unidade Local de Saúde de São José, Lisbon, PortugalDepartment of Dermatology and Venereology, Hospital Santo António dos Capuchos, Unidade Local de Saúde de São José, São José, PortugalDepartment of Dermatology and Venereology, Hospital de Santo António dos Capuchos, Unidade Local de Saúde de São José, Lisbon, Portugal; Department of Dermatology and Venereology, NOVA Medical School, NOVA University of Lisbon, Lisbon, PortugalDermatology and Venereology Department, Hospital de Santo António dos Capuchos, Unidade Local de Saúde de São José, Lisbon, PortugalTakayasu’s arteritis (TA) is a vasculitis that affects large vessels. Rarely, microcirculation is involved, sometimes with cutaneous manifestations. Inflammation of small vessels of the skin can present as erythema nodosum-like lesions and granulomatous cutaneous vasculitis, among others. We describe the case of a 29-year-old woman with a diagnosis of TA confirmed by angio-CT. She was referred to a dermatology appointment due to a skin condition characterized by centimetric, erythematous, painful, and nonulcerated nodules on the soles and inner edges of the feet. Clinical and analytical criteria of active disease were met, despite implemented corticotherapy. Cutaneous biopsy showed panniculitis and leukocytoclastic vasculitis. Autoimmune vasculitis and cryoglobulinemia panels were negative. Erythema nodosum-like subcutaneous nodules have been described in TA, possibly preceding other disease manifestations or as markers of disease activity. An early correlation with constitutional and cardiovascular symptoms may lead to earlier diagnosis and prompt control of disease activity.Takayasu’s arteritis (TA) is a vasculitis that affects large vessels. Rarely, microcirculation is involved, sometimes with cutaneous manifestations. Inflammation of small vessels of the skin can present as erythema nodosum-like lesions and granulomatous cutaneous vasculitis, among others. We describe the case of a 29-year-old woman with a diagnosis of TA confirmed by angio-CT. She was referred to a dermatology appointment due to a skin condition characterized by centimetric, erythematous, painful, and nonulcerated nodules on the soles and inner edges of the feet. Clinical and analytical criteria of active disease were met, despite implemented corticotherapy. Cutaneous biopsy showed panniculitis and leukocytoclastic vasculitis. Autoimmune vasculitis and cryoglobulinemia panels were negative. Erythema nodosum-like subcutaneous nodules have been described in TA, possibly preceding other disease manifestations or as markers of disease activity. An early correlation with constitutional and cardiovascular symptoms may lead to earlier diagnosis and prompt control of disease activity. https://www.portuguesejournalofdermatology.com/frame_eng.php?id=199Small vessel vasculitis. Large vessel vasculitis. Cutaneous vasculitis. Granulomatous panniculitis. Takayasuâs arteritis. |
| spellingShingle | Ma. Cristina Fialho Sara Castro Sara Dias Ricardo Veiga Ana Ferreirinha Emanuel Marques Cândida Fernandes Takayasu’s arteritis with involvement of small cutaneous vessels - with regard to a clinical case Revista da Sociedade Portuguesa de Dermatologia e Venereologia Small vessel vasculitis. Large vessel vasculitis. Cutaneous vasculitis. Granulomatous panniculitis. Takayasuâs arteritis. |
| title | Takayasu’s arteritis with involvement of small cutaneous vessels - with regard to a clinical case |
| title_full | Takayasu’s arteritis with involvement of small cutaneous vessels - with regard to a clinical case |
| title_fullStr | Takayasu’s arteritis with involvement of small cutaneous vessels - with regard to a clinical case |
| title_full_unstemmed | Takayasu’s arteritis with involvement of small cutaneous vessels - with regard to a clinical case |
| title_short | Takayasu’s arteritis with involvement of small cutaneous vessels - with regard to a clinical case |
| title_sort | takayasu s arteritis with involvement of small cutaneous vessels with regard to a clinical case |
| topic | Small vessel vasculitis. Large vessel vasculitis. Cutaneous vasculitis. Granulomatous panniculitis. Takayasuâs arteritis. |
| url | https://www.portuguesejournalofdermatology.com/frame_eng.php?id=199 |
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