Comparative in vitro effects of novel and conventional parasiticides on Thaparocleidus vistulensis (Siwak, 1932) (Monopisthocotyla) parasitizing European catfish (Silurus glanis)
This in vitro study compares the effects of the novel biological parasiticide Biokos (BIO) to the conventional anthelmintics Praziquantel (PZQ) and Mebendazole (MBZ) on the gill parasitic monopisthocotylan Thaparocleidus vistulensis (Siwak, 1932), a species-specific parasite of European catfish (Sil...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-09-01
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| Series: | Aquaculture Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352513425003382 |
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| author | Wan Muhammad Hazim Wan Sajiri Csaba Székely István Czeglédi Kurt Buchmann Boglárka Sellyei |
| author_facet | Wan Muhammad Hazim Wan Sajiri Csaba Székely István Czeglédi Kurt Buchmann Boglárka Sellyei |
| author_sort | Wan Muhammad Hazim Wan Sajiri |
| collection | DOAJ |
| description | This in vitro study compares the effects of the novel biological parasiticide Biokos (BIO) to the conventional anthelmintics Praziquantel (PZQ) and Mebendazole (MBZ) on the gill parasitic monopisthocotylan Thaparocleidus vistulensis (Siwak, 1932), a species-specific parasite of European catfish (Silurus glanis). Parasites were exposed to long-term treatment and tested at concentrations of 0, 1, 5, 10, 20, 40, 60, 80, and 100 mg/L. The antiparasitic effects were observed at all life cycle stages, including eggs, oncomiracidia, developing juvenile, and adult monopisthocotylans. In vitro assays demonstrated MBZ to be the most effective in inhibiting the development of eggs with 100 % efficacy. Treatment of BIO was proven effective in targeting the oncomiracidia life stage compared to the others. Higher concentrations are required for all antiparasitic treatments to show their effectiveness against developing juvenile and adult T. vistulensis. This suggests that strategic combinations of the parasiticides may elevate efficacy. |
| format | Article |
| id | doaj-art-c5b9d877f4ce4c8488c768c7275a2f94 |
| institution | Kabale University |
| issn | 2352-5134 |
| language | English |
| publishDate | 2025-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Aquaculture Reports |
| spelling | doaj-art-c5b9d877f4ce4c8488c768c7275a2f942025-08-20T04:00:32ZengElsevierAquaculture Reports2352-51342025-09-014310295210.1016/j.aqrep.2025.102952Comparative in vitro effects of novel and conventional parasiticides on Thaparocleidus vistulensis (Siwak, 1932) (Monopisthocotyla) parasitizing European catfish (Silurus glanis)Wan Muhammad Hazim Wan Sajiri0Csaba Székely1István Czeglédi2Kurt Buchmann3Boglárka Sellyei4HUN-REN Veterinary Medical Research Institute, 21, Hungária krt, Budapest H-1143, Hungary; Doctoral School of Animal Biotechnology and Animal Science, Hungarian University of Agriculture and Life Sciences, 1. Páter Károly str., Gödöllő H-2100, HungaryHUN-REN Veterinary Medical Research Institute, 21, Hungária krt, Budapest H-1143, HungaryHUN-REN Balaton Limnological Research Institute, Klebelsberg Kuno u. 3, Tihany, 8237, HungaryDepartment of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Frederiksberg C, DenmarkHUN-REN Veterinary Medical Research Institute, 21, Hungária krt, Budapest H-1143, Hungary; Corresponding author.This in vitro study compares the effects of the novel biological parasiticide Biokos (BIO) to the conventional anthelmintics Praziquantel (PZQ) and Mebendazole (MBZ) on the gill parasitic monopisthocotylan Thaparocleidus vistulensis (Siwak, 1932), a species-specific parasite of European catfish (Silurus glanis). Parasites were exposed to long-term treatment and tested at concentrations of 0, 1, 5, 10, 20, 40, 60, 80, and 100 mg/L. The antiparasitic effects were observed at all life cycle stages, including eggs, oncomiracidia, developing juvenile, and adult monopisthocotylans. In vitro assays demonstrated MBZ to be the most effective in inhibiting the development of eggs with 100 % efficacy. Treatment of BIO was proven effective in targeting the oncomiracidia life stage compared to the others. Higher concentrations are required for all antiparasitic treatments to show their effectiveness against developing juvenile and adult T. vistulensis. This suggests that strategic combinations of the parasiticides may elevate efficacy.http://www.sciencedirect.com/science/article/pii/S2352513425003382Thaparocleidus vistulensisSilurus glanisAntiparasitic efficacyBiokosPraziquantelMebendazole |
| spellingShingle | Wan Muhammad Hazim Wan Sajiri Csaba Székely István Czeglédi Kurt Buchmann Boglárka Sellyei Comparative in vitro effects of novel and conventional parasiticides on Thaparocleidus vistulensis (Siwak, 1932) (Monopisthocotyla) parasitizing European catfish (Silurus glanis) Aquaculture Reports Thaparocleidus vistulensis Silurus glanis Antiparasitic efficacy Biokos Praziquantel Mebendazole |
| title | Comparative in vitro effects of novel and conventional parasiticides on Thaparocleidus vistulensis (Siwak, 1932) (Monopisthocotyla) parasitizing European catfish (Silurus glanis) |
| title_full | Comparative in vitro effects of novel and conventional parasiticides on Thaparocleidus vistulensis (Siwak, 1932) (Monopisthocotyla) parasitizing European catfish (Silurus glanis) |
| title_fullStr | Comparative in vitro effects of novel and conventional parasiticides on Thaparocleidus vistulensis (Siwak, 1932) (Monopisthocotyla) parasitizing European catfish (Silurus glanis) |
| title_full_unstemmed | Comparative in vitro effects of novel and conventional parasiticides on Thaparocleidus vistulensis (Siwak, 1932) (Monopisthocotyla) parasitizing European catfish (Silurus glanis) |
| title_short | Comparative in vitro effects of novel and conventional parasiticides on Thaparocleidus vistulensis (Siwak, 1932) (Monopisthocotyla) parasitizing European catfish (Silurus glanis) |
| title_sort | comparative in vitro effects of novel and conventional parasiticides on thaparocleidus vistulensis siwak 1932 monopisthocotyla parasitizing european catfish silurus glanis |
| topic | Thaparocleidus vistulensis Silurus glanis Antiparasitic efficacy Biokos Praziquantel Mebendazole |
| url | http://www.sciencedirect.com/science/article/pii/S2352513425003382 |
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