Kinetic Analysis of [C]Vorozole Binding in the Human Brain with Positron Emission Tomography

Kinetic Analysis of [C]Vorozole Binding in the Human Brain with Positron Emission Tomography

Using positron emission tomography, we investigated the kinetics of [ 11 C]vorozole ([ 11 C]VOR), a radiotracer for the enzyme aromatase that catalyzes the last step in estrogen biosynthesis. Six subjects were scanned under baseline conditions followed by retest 2 weeks later. The retest was followe...

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Bibliographic Details
Main Authors: Jean Logan, Sung Won Kim, Deborah Pareto, Frank Telang, Gene-Jack Wang, Joanna S. Fowler, Anat Biegon
Format: Article
Language:English
Published: SAGE Publishing 2014-05-01
Series:Molecular Imaging
Online Access:https://doi.org/10.2310/7290.2014.00004
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