β-Hydroxybutyrate-induced mitochondrial DNA (mtDNA) release mediated innate inflammatory response in bovine mammary epithelial cells by inhibiting autophagy
Abstract Background In perinatal dairy cows, ketosis is a prevalent metabolic disorder that lowers milk output and performance. Mitochondrial dysfunction and chronic inflammation in mammary tissue are linked to elevated blood ketone levels, particularly β-hydroxybutyrate (BHB). Recent research has l...
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Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2025-02-01
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Series: | Journal of Animal Science and Biotechnology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s40104-024-01143-z |
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